SCHEMBL17415232

SCHEMBL17415232

C[Si](C)=[Hf](C)(C)(C1C=Cc2c(-c3cccc4ccccc34)cccc21)C1C=Cc2c(-c3cccc4ccccc34)cccc21

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.33
SLC6A4 P31645 2/20 0.31
ALDH1A1 P00352 2/20 0.31
MAPT P10636 2/20 0.31
HPGD P15428 2/20 0.31
KDM4E B2RXH2 1/20 0.31
TDP2 O95551 1/20 0.31
ALOX12 P18054 1/20 0.31
MAPK1 P28482 1/20 0.31
CASP3 P42574 1/20 0.31
HTT P42858 1/20 0.31
GALK1 P51570 1/20 0.31
BLM P54132 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
SENP8 Q96LD8 1/20 0.31
SENP7 Q9BQF6 1/20 0.31
SENP6 Q9GZR1 1/20 0.31
KDM4C Q9H3R0 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
SLC6A2 P23975 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17415304 0.86 NPC1 (0.32) MAPT
SCHEMBL17415496 0.86 SLC6A4 (0.35) SLC6A4ALDH1A1MAPTHPGDHTR7
SCHEMBL17415061 0.83 PBRM1 (0.31)
SCHEMBL17414972 0.82 CHRNB2 (0.33)
SCHEMBL17386685 0.81 MAPK1 (0.33) SLC6A4ALDH1A1MAPTHPGDKDM4E
SCHEMBL17387031 0.81 HTR7 (0.33) KDM1AMAPTHTR1AHTR7
SCHEMBL17415036 0.81 GSTP1 (0.36) SLC6A4SLC6A2SLC6A3
SCHEMBL17387250 0.81 HTR7 (0.33) KDM1AALDH1A1MAPTHPGDKDM4E
SCHEMBL17416024 0.80 CSNK2A2 (0.30)
SCHEMBL17415569 0.80 HTR2A (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2966096-B1 METHOD FOR PRODUCING ETHYLENE/ -OLEFIN COPOLYMER JAPAN POLYETHYLENE CORP (JP) 2017-04-26 EP disclosed
EP-2966096-A1 METHOD FOR PRODUCING ETHYLENE/ -OLEFIN COPOLYMER Japan Polyethylene Corporation (JP) 2016-01-13 EP disclosed