SCHEMBL17415544

SCHEMBL17415544

CC(C)(C)c1ccc(-c2cccc3c2C=CC3[Hf](C)(C)(C)(C)(=[SiH2])C2C=Cc3c(-c4ccc(C(C)(C)C)cc4)cccc32)cc1

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.33
CREBBP Q92793 1/20 0.33
S1PR1 P21453 1/20 0.32
NPC1 O15118 1/20 0.30
LMNA P02545 1/20 0.30
TP53 P04637 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17415221 0.90 BRD4 (0.32) BRD4CREBBPS1PR1
SCHEMBL17415891 0.88 KIF11 (0.33) RAB9ASMN1; SMN2
SCHEMBL17415165 0.88 RXRA (0.31)
SCHEMBL17415605 0.87 BRD4 (0.31) BRD4CREBBP
SCHEMBL17415475 0.87 AKR1C3 (0.33) BRD4CREBBP
SCHEMBL17414898 0.87 BRD4 (0.31) BRD4CREBBP
SCHEMBL17415931 0.87 KIF11 (0.36)
SCHEMBL17415254 0.86 S1PR1 (0.32) BRD4CREBBPS1PR1
SCHEMBL17415194 0.86 S1PR1 (0.32) BRD4CREBBPS1PR1
SCHEMBL17414910 0.85 BRD4 (0.32) BRD4CREBBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2966096-B1 METHOD FOR PRODUCING ETHYLENE/ -OLEFIN COPOLYMER JAPAN POLYETHYLENE CORP (JP) 2017-04-26 EP disclosed
EP-2966096-A1 METHOD FOR PRODUCING ETHYLENE/ -OLEFIN COPOLYMER Japan Polyethylene Corporation (JP) 2016-01-13 EP disclosed