SCHEMBL17415679

SCHEMBL17415679

CCCCSC(=O)Nc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 1.00
NPSR1 Q6W5P4 1/20 1.00
EPHX1 P07099 3/20 0.51
HTT P42858 1/20 0.51
HDAC3 O15379 2/20 0.51
HDAC1 Q13547 2/20 0.51
HDAC2 Q92769 2/20 0.51
HDAC4 P56524 1/20 0.51
HDAC7 Q8WUI4 1/20 0.51
HDAC10 Q969S8 1/20 0.51
HDAC11 Q96DB2 1/20 0.51
HDAC8 Q9BY41 1/20 0.51
HDAC6 Q9UBN7 1/20 0.51
HDAC9 Q9UKV0 1/20 0.51
HDAC5 Q9UQL6 1/20 0.51
ICMT O60725 1/20 0.50
ALB P02768 1/20 0.50
TRPV1 Q8NER1 1/20 0.49
CYP2C19 P33261 1/20 0.49
RECQL P46063 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17416072 0.95 ALDH1A1 (0.90) ALDH1A1NPSR1EPHX1HTTHDAC3
SCHEMBL14602860 0.93 ALDH1A1 (0.88) ALDH1A1NPSR1EPHX1HTTHDAC3
SCHEMBL14602832 0.93 ALDH1A1 (0.88) ALDH1A1NPSR1EPHX1HTTHDAC3
SCHEMBL14602825 0.93 ALDH1A1 (0.88) ALDH1A1NPSR1EPHX1HTTHDAC3
SCHEMBL5246578 0.93 ALDH1A1 (0.88) ALDH1A1NPSR1EPHX1HTTHDAC3
SCHEMBL17415980 0.93 ALDH1A1 (0.88) ALDH1A1NPSR1EPHX1HTTHDAC3
SCHEMBL14602862 0.93 ALDH1A1 (0.88) ALDH1A1NPSR1EPHX1HTTHDAC3
SCHEMBL14602847 0.93 ALDH1A1 (0.88) ALDH1A1NPSR1EPHX1HTTHDAC3
SCHEMBL14602828 0.93 ALDH1A1 (0.88) ALDH1A1NPSR1EPHX1HTTHDAC3
SCHEMBL17416187 0.93 ALDH1A1 (0.88) ALDH1A1NPSR1EPHX1HTTHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11046645-B2 Isothiocyanate production method, composition for transporting and storing N-substituted O-substituted thiocarbamate, and isothiocyanate composition ASAHI KASEI CHEMICALS CORPORATION (JP) 2021-06-29 US disclosed
EP-3363785-B1 ISOTHIOCYANATE PRODUCTION METHODS ASAHI CHEMICAL IND (JP) 2020-09-16 EP disclosed
US-20190233371-A1 Isothiocyanate Production Method, Composition for Transporting and Storing N-Substituted O-Substituted Thiocarbamate, and Isothiocyanate Composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2019-08-01 US disclosed
EP-3214071-B1 ISOTHIOCYANATE COMPOSITION ASAHI CHEMICAL IND (JP) 2019-07-03 EP disclosed
US-10308601-B2 Isothiocyanate production method, composition for transporting and storing N-substituted O-substituted thiocarbamate, and isothiocyanate composition ASAHI KASEI CHEMICALS CORPORATION (JP) 2019-06-04 US disclosed
EP-3363785-A1 ISOTHIOCYANATE PRODUCTION METHODS Asahi Kasei Chemicals Corporation (JP) 2018-08-22 EP disclosed
EP-3214071-A1 ISOTHIOCYANATE COMPOSITION Asahi Kasei Chemicals Corporation (JP) 2017-09-06 EP disclosed
US-20160016901-A1 ISOTHIOCYANATE PRODUCTION METHOD, COMPOSITION FOR TRANSPORTING AND STORING N-SUBSTITUTED O-SUBSTITUTED THIOCARBAMATE, AND ISOTHIOCYANATE COMPOSITION ASAHI KASEI CHEMICALS CORPORATION (JP) 2016-01-21 US disclosed
EP-2966060-A1 ISOTHIOCYANATE PRODUCTION METHOD, COMPOSITION FOR TRANSPORTING AND STORING N-SUBSTITUTED O-SUBSTITUTED THIOCARBAMATE, AND ISOTHIOCYANATE COMPOSITION Asahi Kasei Chemicals Corporation (JP) 2016-01-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11046645-B2 Isothiocyanate production method, composition for transporting and storing N-substituted O-substituted thiocarbamate, and isothiocyanate composition TST, SLCO4C1, SLCO2B1 ALDH1A1 723/4885NPSR1 2962/4885EPHX1 1137/4885
US-20160016901-A1 ISOTHIOCYANATE PRODUCTION METHOD, COMPOSITION FOR TRANSPORTING AND STORING N-SUBSTITUTED O-SUBSTITUTED THIOCARBAMATE, AND ISOTHIOCYANATE COMPOSITION TST, SLCO4C1, SLCO2B1 ALDH1A1 723/4885NPSR1 2962/4885EPHX1 1137/4885
US-20190233371-A1 Isothiocyanate Production Method, Composition for Transporting and Storing N-Substituted O-Substituted Thiocarbamate, and Isothiocyanate Composition TST, SLCO4C1, SLCO2B1 ALDH1A1 723/4885NPSR1 2962/4885EPHX1 1137/4885
US-10308601-B2 Isothiocyanate production method, composition for transporting and storing N-substituted O-substituted thiocarbamate, and isothiocyanate composition TST, SLCO4C1, SLCO2B1 ALDH1A1 723/4885NPSR1 2962/4885EPHX1 1137/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.