SCHEMBL17415951

SCHEMBL17415951

CC[Hf](C)(C)(=[SiH2])(CC)(C1C=Cc2c(-c3ccc4ccccc4c3)cccc21)C1C=Cc2c(-c3ccc4ccccc4c3)cccc21

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GSTP1 P09211 1/20 0.34
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
HDAC4 P56524 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
AKR1C3 P42330 2/20 0.32
AKR1C2 P52895 2/20 0.32
S1PR4 O95977 2/20 0.31
S1PR5 Q9H228 2/20 0.31
MET P08581 1/20 0.31
CNR2 P34972 1/20 0.30
HSD17B1 P14061 1/20 0.30
HSD17B2 P37059 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17415040 0.88 GSTP1 (0.37) GSTP1SLC6A2SLC6A4SLC6A3HDAC4
SCHEMBL17415979 0.85 HTR1A (0.32)
SCHEMBL17415006 0.83 AKR1C3 (0.37) GSTP1SLC6A2SLC6A4SLC6A3HDAC4
SCHEMBL17415864 0.83 BRD4 (0.31)
SCHEMBL17414958 0.83 CA12 (0.31) METCNR2
SCHEMBL17415963 0.83
SCHEMBL17415504 0.82 BRD4 (0.33)
SCHEMBL17415486 0.82 ABL1 (0.35) HDAC4HDAC2HDAC8
SCHEMBL17415499 0.81 HTR7 (0.36) SLC6A2SLC6A4SLC6A3
SCHEMBL17415801 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2966096-B1 METHOD FOR PRODUCING ETHYLENE/ -OLEFIN COPOLYMER JAPAN POLYETHYLENE CORP (JP) 2017-04-26 EP disclosed
EP-2966096-A1 METHOD FOR PRODUCING ETHYLENE/ -OLEFIN COPOLYMER Japan Polyethylene Corporation (JP) 2016-01-13 EP disclosed