SCHEMBL17416092

SCHEMBL17416092

CCCCCCCCCCCCCCCCCCOC(=S)NCCCCCCNC(=S)OCCCCCCCCCCCCCCCCCC

nearest known ligand 0.53

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ACHE P22303 12/20 0.53
CA12 O43570 3/20 0.52
CA1 P00915 3/20 0.52
CA2 P00918 3/20 0.52
CA9 Q16790 3/20 0.52
EPHX1 P07099 4/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17415823 1.00 ACHE (0.53) ACHECA12CA1CA2CA9
SCHEMBL17416108 1.00 ACHE (0.53) ACHECA12CA1CA2CA9
SCHEMBL17415691 1.00 ACHE (0.53) ACHECA12CA1CA2CA9
SCHEMBL17416051 1.00 ACHE (0.53) ACHECA12CA1CA2CA9
SCHEMBL17436874 1.00 ACHE (0.53) ACHECA12CA1CA2CA9
Ammonia Solution, Strong SCHEMBL5822821 0.98 ACHE (0.52) ACHECA12CA1CA2CA9
SCHEMBL11614911 0.98 ACHE (0.52) ACHECA12CA1CA2CA9
SCHEMBL11382450 0.98 ACHE (0.52) ACHECA12CA1CA2CA9
SCHEMBL2495229 0.98 CA12 (0.52) ACHECA12CA1CA2CA9
SCHEMBL6692193 0.96 ACHE (0.58) ACHECA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11046645-B2 Isothiocyanate production method, composition for transporting and storing N-substituted O-substituted thiocarbamate, and isothiocyanate composition ASAHI KASEI CHEMICALS CORPORATION (JP) 2021-06-29 US disclosed
EP-3363785-B1 ISOTHIOCYANATE PRODUCTION METHODS ASAHI CHEMICAL IND (JP) 2020-09-16 EP disclosed
US-20190233371-A1 Isothiocyanate Production Method, Composition for Transporting and Storing N-Substituted O-Substituted Thiocarbamate, and Isothiocyanate Composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2019-08-01 US disclosed
EP-3214071-B1 ISOTHIOCYANATE COMPOSITION ASAHI CHEMICAL IND (JP) 2019-07-03 EP disclosed
US-10308601-B2 Isothiocyanate production method, composition for transporting and storing N-substituted O-substituted thiocarbamate, and isothiocyanate composition ASAHI KASEI CHEMICALS CORPORATION (JP) 2019-06-04 US disclosed
EP-3363785-A1 ISOTHIOCYANATE PRODUCTION METHODS Asahi Kasei Chemicals Corporation (JP) 2018-08-22 EP disclosed
EP-3214071-A1 ISOTHIOCYANATE COMPOSITION Asahi Kasei Chemicals Corporation (JP) 2017-09-06 EP disclosed
US-20160016901-A1 ISOTHIOCYANATE PRODUCTION METHOD, COMPOSITION FOR TRANSPORTING AND STORING N-SUBSTITUTED O-SUBSTITUTED THIOCARBAMATE, AND ISOTHIOCYANATE COMPOSITION ASAHI KASEI CHEMICALS CORPORATION (JP) 2016-01-21 US disclosed
EP-2966060-A1 ISOTHIOCYANATE PRODUCTION METHOD, COMPOSITION FOR TRANSPORTING AND STORING N-SUBSTITUTED O-SUBSTITUTED THIOCARBAMATE, AND ISOTHIOCYANATE COMPOSITION Asahi Kasei Chemicals Corporation (JP) 2016-01-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11046645-B2 Isothiocyanate production method, composition for transporting and storing N-substituted O-substituted thiocarbamate, and isothiocyanate composition TST, SLCO4C1, SLCO2B1 ACHE 1844/4885CA12 1513/4885CA1 1480/4885
US-20160016901-A1 ISOTHIOCYANATE PRODUCTION METHOD, COMPOSITION FOR TRANSPORTING AND STORING N-SUBSTITUTED O-SUBSTITUTED THIOCARBAMATE, AND ISOTHIOCYANATE COMPOSITION TST, SLCO4C1, SLCO2B1 ACHE 1844/4885CA12 1513/4885CA1 1480/4885
US-20190233371-A1 Isothiocyanate Production Method, Composition for Transporting and Storing N-Substituted O-Substituted Thiocarbamate, and Isothiocyanate Composition TST, SLCO4C1, SLCO2B1 ACHE 1844/4885CA12 1513/4885CA1 1480/4885
US-10308601-B2 Isothiocyanate production method, composition for transporting and storing N-substituted O-substituted thiocarbamate, and isothiocyanate composition TST, SLCO4C1, SLCO2B1 ACHE 1844/4885CA12 1513/4885CA1 1480/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.