SCHEMBL1741640

SCHEMBL1741640

CCCCCCCCCCCC1=NC(CC)CN1

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
PKM P14618 1/20 0.33
HPGD P15428 1/20 0.33
KCNH2 Q12809 1/20 0.32
NAAA Q02083 5/20 0.32
GAA P10253 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10617495 1.00 ALDH1A1 (0.33) ALDH1A1PKMHPGDKCNH2NAAA
SCHEMBL8721243 0.92 EPHX2 (0.38) ALDH1A1
SCHEMBL20954129 0.87 SCN2A (0.36) ALDH1A1
SCHEMBL20954138 0.87 SCN2A (0.36) ALDH1A1
SCHEMBL11138004 0.87 SCN2A (0.36) ALDH1A1
SCHEMBL4665788 0.87 SCN2A (0.36) ALDH1A1
SCHEMBL7698170 0.85 NOS1 (0.36)
SCHEMBL324903 0.83 GBA1 (0.35) ALDH1A1NAAAGAA
SCHEMBL1648426 0.83 GBA1 (0.35) ALDH1A1NAAAGAA
SCHEMBL7778401 0.83 HTR2A (0.36) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0296199-A1 HETEROCYCLIC COMPOUNDS FOR TRANSDERMAL USE RAJADHYAKSHA, Vithal J. (US) 1988-12-28 EP claimed
WO-1988004938-A1 HETEROCYCLIC COMPOUNDS FOR TRANSDERMAL USE RAJADHYAKSHA VITHAL J (US) 1988-07-14 WO claimed
EP-4569023-A1 COMBINATION OF CATALYTIC COMPONENTS PolyU GmbH (DE) 2025-06-18 EP disclosed
WO-2024033348-A1 COMBINATION OF CATALYTIC COMPONENTS POLYU GMBH (DE) 2024-02-15 WO disclosed
EP-4321573-A1 COMBINATION OF CATALYTIC COMPONENTS PolyU GmbH (DE) 2024-02-14 EP disclosed
EP-2388297-B1 CURABLE COMPOSITION AND CURED OBJECT FORMED THEREFROM KANEKA CORP (JP) 2020-08-19 EP disclosed
CN-106574114-B Curable organopolysiloxane composition 瓦克化学股份公司 2019-10-15 CN disclosed
US-10301433-B2 Curable organopolysiloxane compositions WACKER CHEMIE AG (DE) 2019-05-28 US disclosed
EP-3172178-B1 CURABLE ORGANOPOLYSILOXANE COMPOSITIONS WACKER CHEMIE AG (DE) 2018-09-12 EP disclosed
US-20170210856-A1 CURABLE ORGANOPOLYSILOXANE COMPOSITIONS WACKER CHEMIE AG (DE) 2017-07-27 US disclosed
EP-1939257-B1 CURABLE COMPOSITION KANEKA CORP (JP) 2017-06-21 EP disclosed
CN-106574114-A Curable organopolysiloxane compositions 瓦克化学股份公司 2017-04-19 CN disclosed
EP-2388297-A1 CURABLE COMPOSITION AND CURED OBJECT FORMED THEREFROM Kaneka Corporation (JP) 2011-11-23 EP disclosed
US-8013079-B2 Curable composition KANEKA CORPORATION (JP) 2011-09-06 US disclosed
US-20100036049-A1 CURABLE COMPOSITION KANEKA CORPORATION 2010-02-11 US disclosed
EP-1939257-A1 CURABLE COMPOSITION Kaneka Corporation (JP) 2008-07-02 EP disclosed