Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 16/20 | 0.72 |
| ▸ | RORB | Q92753 | 1/20 | 0.72 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL175183 | 0.84 | RORC (1.00) | RORCRORB | |
| SCHEMBL175290 | 0.82 | RORC (0.81) | RORCRORB | |
| SCHEMBL175300 | 0.80 | RORC (0.89) | RORCRORB | |
| SCHEMBL178242 | 0.79 | RORC (0.80) | RORCRORB | |
| SCHEMBL175258 | 0.79 | RORC (0.83) | RORCRORB | |
| SCHEMBL175486 | 0.78 | RORC (0.93) | RORCRORB | |
| SCHEMBL175371 | 0.78 | RORC (1.00) | RORCRORB | |
| SCHEMBL175194 | 0.78 | RORC (0.86) | RORCRORB | |
| SCHEMBL175493 | 0.78 | RORC (1.00) | RORCRORB | |
| SCHEMBL175661 | 0.77 | RORC (0.84) | RORCRORB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012028100-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-03-08 | — | — | WO | disclosed |
| WO-2012028100-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-03-08 | — | — | WO | disclosed |