Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9102868 | 0.89 | TSHR (0.40) | NPC1LMNATP53KDM4ERAB9A | |
| SCHEMBL18091874 | 0.89 | MAPT (0.43) | KCNK3KCNK9LMNAHSD17B10HPGD | |
| SCHEMBL9100311 | 0.87 | RAB9A (0.43) | HDAC1HDAC6NPC1LMNARAB9A | |
| SCHEMBL18091870 | 0.87 | NPC1 (0.35) | CTSDHDAC1HDAC6NPC1KCNK3 | |
| SCHEMBL2482845 | 0.86 | ABCB1 (0.51) | NPC1RAB9A | |
| SCHEMBL27356523 | 0.86 | KDM4E (0.39) | NPC1LMNAHPGDKDM4ERAB9A | |
| SCHEMBL18091865 | 0.85 | NPC1 (0.48) | NPC1LMNAHPGDKDM4ERAB9A | |
| SCHEMBL17416645 | 0.84 | KMT2A (0.37) | LMNAHPGDRXFP1KDM4E | |
| SCHEMBL17025773 | 0.83 | POLB (0.43) | LMNAKDM4ERAB9A | |
| SCHEMBL18091859 | 0.83 | CTNNB1 (0.42) | NPC1HPGDTP53RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2463269-B1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | INTREXON CORP (US) | 2016-09-28 | — | — | EP | disclosed |
| EP-2460786-B1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | INTREXON CORP (US) | 2016-01-13 | — | — | EP | disclosed |