Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17416629 | 0.84 | CTSD (0.43) | HPGDKDM4ERXFP1LMNA | |
| SCHEMBL9101240 | 0.82 | MAPK1 (0.43) | KMT2AMEN1KDM4ECD274LMNA | |
| SCHEMBL17025773 | 0.82 | POLB (0.43) | KMT2AMEN1POLBTHRBKDM4E | |
| SCHEMBL2482845 | 0.81 | ABCB1 (0.51) | ABCB1 | |
| SCHEMBL5053826 | 0.80 | ABCB1 (0.51) | KMT2AP2RX7ABCB1 | |
| SCHEMBL9100311 | 0.80 | RAB9A (0.43) | GAAABCB1MAPTLMNA | |
| SCHEMBL18091874 | 0.79 | MAPT (0.43) | KMT2AMEN1POLBHPGDKDM4E | |
| SCHEMBL9102868 | 0.79 | TSHR (0.40) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL27356523 | 0.78 | KDM4E (0.39) | KMT2AMEN1ALDH1A1HPGDKDM4E | |
| SCHEMBL18091865 | 0.78 | NPC1 (0.48) | KMT2AMEN1ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2463269-B1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | INTREXON CORP (US) | 2016-09-28 | — | — | EP | disclosed |
| EP-2460786-B1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | INTREXON CORP (US) | 2016-01-13 | — | — | EP | disclosed |