Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TOP1 | P11387 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7067587 | 0.84 | ABCB1 (0.64) | ABCB1NPC1RAB9AKCNK3KCNK9 | |
| SCHEMBL17416606 | 0.80 | ABCB1 (0.56) | ABCB1NPC1RAB9AKCNK3KCNK9 | |
| SCHEMBL9104050 | 0.80 | ABCB1 (0.48) | ABCB1ACHESMN1; SMN2 | |
| SCHEMBL17416628 | 0.80 | ABCB1 (0.61) | ABCB1 | |
| SCHEMBL5064249 | 0.80 | ABCB1 (0.73) | ABCB1 | |
| SCHEMBL17416624 | 0.76 | ABCB1 (0.53) | ABCB1NPC1RAB9AKCNK3KCNK9 | |
| SCHEMBL9099071 | 0.76 | ABCB1 (0.53) | ABCB1NPC1RAB9AKCNK3KCNK9 | |
| SCHEMBL9102505 | 0.75 | ABCB1 (0.41) | ABCB1TSHRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17416625 | 0.75 | ABCB1 (0.52) | ABCB1NPC1RAB9AKCNK3KCNK9 | |
| SCHEMBL9099193 | 0.75 | ABCB1 (0.49) | ABCB1KCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460786-B1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | INTREXON CORP (US) | 2016-01-13 | — | — | EP | disclosed |