Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EED | O75530 | 1/20 | 0.36 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.36 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.36 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.36 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7067587 | 0.86 | ABCB1 (0.64) | ABCB1 | |
| SCHEMBL17416606 | 0.83 | ABCB1 (0.56) | ABCB1 | |
| SCHEMBL18091856 | 0.80 | ABCB1 (0.43) | ABCB1ALDH1A1SMN1; SMN2UTS2RGRM5 | |
| SCHEMBL17416630 | 0.80 | ABCB1 (0.46) | ABCB1SMN1; SMN2ACHE | |
| SCHEMBL9102771 | 0.80 | ABCB1 (0.64) | ABCB1 | |
| SCHEMBL5062707 | 0.80 | ABCB1 (0.77) | ABCB1 | |
| SCHEMBL9237588 | 0.78 | P2RX7 (0.40) | ABCB1 | |
| SCHEMBL17416624 | 0.76 | ABCB1 (0.53) | ABCB1 | |
| SCHEMBL9099071 | 0.76 | ABCB1 (0.53) | ABCB1 | |
| SCHEMBL9102505 | 0.75 | ABCB1 (0.41) | ABCB1ALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460786-A1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | Intrexon Corporation (US) | 2012-06-06 | — | — | EP | disclosed |