SCHEMBL17416792

SCHEMBL17416792

CC1(C)CC=C(c2cc(C3(OCCN4C=CC=CC4)CCOCC3)ccc2C(N)=O)CC1

nearest known ligand 0.43

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CSF1R P07333 1/20 0.31
KIT P10721 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17416793 0.89
SCHEMBL16320617 0.85 CSF1R (0.38) CSF1RKIT
SCHEMBL16320443 0.82 LMNA (0.38) CSF1RKIT
Trifluoroacetic Acid SCHEMBL5471985 0.77 CSF1R (0.41) CSF1RKIT
SCHEMBL3901818 0.76 CSF1R (0.35) CSF1R
SCHEMBL3164430 0.74
SCHEMBL16319873 0.74
SCHEMBL3901833 0.74
SCHEMBL3913620 0.74
SCHEMBL3901245 0.74 ALOX5 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2016070-B1 INHIBITORS OF C-FMS KINASE JANSSEN PHARMACEUTICA NV (BE) 2016-01-13 EP disclosed