Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 3/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 7/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | CDC7 | O00311 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17416814 | 0.75 | GAA (0.38) | — | |
| SCHEMBL7416358 | 0.65 | NOTUM (0.41) | NOTUM | |
| Hydrochloric Acid SCHEMBL7416277 | 0.64 | NOTUM (0.40) | NOTUM | |
| SCHEMBL9919049 | 0.61 | GAA (0.38) | NOTUM | |
| SCHEMBL7420370 | 0.60 | HSD17B10 (0.39) | ARNOTUM | |
| SCHEMBL5655667 | 0.59 | NOTUM (0.41) | NOTUM | |
| SCHEMBL9919035 | 0.57 | DRD1 (0.41) | ARNOTUM | |
| SCHEMBL7420610 | 0.57 | GRIA1 (0.39) | NOTUM | |
| SCHEMBL9919078 | 0.56 | NOTUM (0.35) | NOTUM | |
| SCHEMBL9919095 | 0.55 | DRD1 (0.35) | ARNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1891067-B1 | ANDROGEN RECEPTOR MODULATOR COMPOUNDS AND METHODS | LIGAND PHARM INC (US) | 2016-01-13 | — | — | EP | disclosed |