Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | RHEB | Q15382 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7416277 | 0.98 | NOTUM (0.40) | NOTUMHTR2AHTR2CKDM4EALOX15 | |
| SCHEMBL7420610 | 0.90 | GRIA1 (0.39) | NOTUMHTR2AHTR2CKDM4EALOX15 | |
| SCHEMBL7420370 | 0.73 | HSD17B10 (0.39) | NOTUMHTR2AHTR2CKDM4EALOX15 | |
| SCHEMBL1009053 | 0.71 | MAOA (0.34) | HTR2AHTR2CKDM4EALOX15MAPK1 | |
| SCHEMBL26569892 | 0.70 | KDM4E (0.50) | KDM4EALDH1A1MAPTRXFP1DHFR | |
| SCHEMBL17426202 | 0.66 | KDM4E (0.46) | KDM4EALDH1A1MAPTRXFP1DHFR | |
| SCHEMBL12278359 | 0.66 | KDM4E (0.46) | KDM4EALDH1A1MAPTRXFP1DHFR | |
| SCHEMBL18527106 | 0.66 | HTR2C (0.39) | HTR2AHTR2CKDM4EALDH1A1MAPT | |
| SCHEMBL17416802 | 0.65 | AR (0.35) | NOTUM | |
| SCHEMBL7415949 | 0.64 | AR (0.40) | HTR2AHTR2CKDM4EMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0656003-A1 | CONDENSED INDOLE DERIVATIVES AS 5HT2C AND 5HT2B ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-06-07 | — | — | EP | disclosed |
| EP-0431968-B1 | Oxetane derivatives, their preparation and their use as anti-fungal or fungicidal agents | SANKYO CO (JP) | 1995-03-15 | — | — | EP | disclosed |
| WO-1994004533-A1 | CONDENSED INDOLE DERIVATIVES AS 5HT2C AND 5HT2B ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-03-03 | — | — | WO | disclosed |