Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | PPP5C | P53041 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3319457 | 0.82 | — | — | |
| SCHEMBL9073688 | 0.74 | — | — | |
| SCHEMBL6179080 | 0.67 | TSHR (0.33) | TSHR | |
| Acetic Acid SCHEMBL7795231 | 0.67 | — | — | |
| Acetic Acid SCHEMBL30063484 | 0.67 | — | — | |
| Acetic Acid SCHEMBL7795226 | 0.67 | FFAR3 (0.88) | FFAR3LCKFYNTSHR | |
| Adamantane SCHEMBL8402827 | 0.65 | FFAR3 (0.54) | FFAR3LCKFYNTSHR | |
| Acetic Acid SCHEMBL1287799 | 0.65 | — | — | |
| Adamantane SCHEMBL27239 | 0.65 | FFAR3 (0.54) | FFAR3LCKFYNTSHR | |
| SCHEMBL11361915 | 0.65 | PPP5C (0.33) | FFAR3PPP5CTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9362527-B2 | Functional film having a hybrid layer of polysiloxane and fine resin particles | Konica Minolta, Inc. (JP) | 2016-06-07 | — | — | US | disclosed |
| US-20160013443-A1 | FUNCTIONAL FILM, METHOD FOR PRODUCING THE SAME, AND ELECTRONIC DEVICE INCLUDING FUNCTIONAL FILM | Konica Minolta, Inc. (JP) | 2016-01-14 | — | — | US | disclosed |