SCHEMBL1741736

SCHEMBL1741736

ClCc1ccccc1C1CC2C=CC1C2

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
TSHR P16473 2/20 0.35
ALDH1A1 P00352 3/20 0.33
TDP1 Q9NUW8 1/20 0.33
HTR2A P28223 1/20 0.30
HTR2C P28335 1/20 0.30
HTR2B P41595 1/20 0.30
LMNA P02545 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
HIF1A Q16665 1/20 0.30
CHRM2 P08172 1/20 0.30
CHRM4 P08173 1/20 0.30
CHRM1 P11229 1/20 0.30
CHRM3 P20309 1/20 0.30
PTGS2 P35354 1/20 0.30
HRH1 P35367 1/20 0.30
KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22194114 0.86 KDM4E (0.38) KDM4EMEN1KMT2ATSHRALDH1A1
SCHEMBL27701951 0.83 KDM4E (0.37) KDM4EMEN1KMT2ATSHRHTR2A
SCHEMBL1266508 0.83 KDM4E (0.40) KDM4EMEN1KMT2ATSHRALDH1A1
SCHEMBL30509733 0.83 KDM4E (0.40) KDM4EMEN1KMT2ATSHRALDH1A1
SCHEMBL29625374 0.77 HTR2A (0.47) KDM4ETSHRHTR2AHTR2CHTR2B
SCHEMBL1739919 0.77 HTR2A (0.47) KDM4ETSHRHTR2AHTR2CHTR2B
SCHEMBL18587142 0.76 HTR2C (0.37) KDM4EMEN1KMT2ATSHRALDH1A1
SCHEMBL3293431 0.73 HTR2A (0.47) KDM4EMEN1KMT2ATSHRALDH1A1
SCHEMBL22194113 0.73 KDM4E (0.34) KDM4EMEN1KMT2ATSHRALDH1A1
SCHEMBL1741315 0.73 KDM1A (0.53) KDM4EMEN1KMT2ATSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2390690-A1 INVERSELY DISPERSIVE RETARDATION FILM, AND LIQUID CRYSTAL DISPLAY DEVICE COMPRISING SAME JX Nippon Oil & Energy Corporation (JP) 2011-11-30 EP disclosed
EP-2060937-A1 RETARDATION FILM, AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME Nippon Oil Corporation (JP) 2009-05-20 EP disclosed