SCHEMBL1266508

SCHEMBL1266508

CCc1ccccc1C1CC2C=CC1C2

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
LMNA P02545 2/20 0.35
TSHR P16473 2/20 0.35
ALDH1A1 P00352 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
HTT P42858 1/20 0.33
CTSB P07858 1/20 0.33
CYP2D6 P10635 1/20 0.32
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30509733 1.00 KDM4E (0.40) KDM4EMEN1KMT2ALMNATSHR
SCHEMBL22194114 0.86 KDM4E (0.38) KDM4EMEN1KMT2ALMNATSHR
SCHEMBL1741736 0.83 KDM4E (0.37) KDM4EMEN1KMT2ALMNATSHR
SCHEMBL27701951 0.83 KDM4E (0.37) KDM4EMEN1KMT2ATSHRSLC6A2
SCHEMBL912359 0.77 HTR2C (0.47) KDM4EMEN1KMT2ATSHRSLC6A2
SCHEMBL29812920 0.77 HTR2C (0.47) KDM4EMEN1KMT2ATSHRSLC6A2
SCHEMBL18587142 0.76 HTR2C (0.37) KDM4EMEN1KMT2ALMNATSHR
SCHEMBL1265478 0.74 GABRA1 (0.35) KDM4EMEN1KMT2ALMNATSHR
SCHEMBL29813196 0.74 GABRA1 (0.35) KDM4EMEN1KMT2ALMNATSHR
SCHEMBL3293431 0.73 HTR2A (0.47) KDM4EMEN1KMT2ALMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0446051-B1 Process for the production of cycloolefin-based random copolymer MITSUI PETROCHEMICAL IND (JP) 1995-11-15 EP claimed
EP-0325260-B1 Random copolymer containing derivative of bicyclo (2.2.1) hept-2-ene compound NIPPON OIL CO LTD (JP) 1994-11-02 EP claimed
US-5142007-A Copolymerizing with ethylene and at least one unsaturated monomer in presence of catalysts and mixed solvent MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-08-25 US claimed
EP-0446051-A1 Process for the production of cycloolefin-based random copolymer MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-09-11 EP claimed
EP-4112671-B1 CYCLOOLEFIN RING-OPENED COPOLYMER, COMPOSITION FOR ELECTRICALLY INSULATING MATERIAL, AND ELECTRICALLY INSULATING MATERIAL ZEON CORP (JP) 2026-04-08 EP disclosed
US-12428521-B2 Cycloolefin ring-opened copolymer, composition for electrically insulating material, and electrically insulating material ZEON CORPORATION (JP) 2025-09-30 US disclosed
WO-2025100415-A1 CYCLIC OLEFIN RING-OPENED POLYMER, CYCLIC OLEFIN RING-OPENED POLYMER HYDRIDE, RESIN COMPOSITION, AND RESIN MOLDED BODY 日本ゼオン株式会社 2025-05-15 WO disclosed
WO-2024127881-A1 CYCLIC OLEFIN RING-OPENED POLYMER HYDRIDE, RESIN COMPOSITION AND FILM 日本ゼオン株式会社 2024-06-20 WO disclosed
WO-2023112921-A1 FLEXIBLE WAVEGUIDE 三井化学株式会社 2023-06-22 WO disclosed
US-20230095059-A1 CYCLOOLEFIN RING-OPENED COPOLYMER, COMPOSITION FOR ELECTRICALLY INSULATING MATERIAL, AND ELECTRICALLY INSULATING MATERIAL ZEON CORPORATION (JP) 2023-03-30 US disclosed
WO-2023276873-A1 CYCLIC OLEFIN POLYMER, CYCLIC OLEFIN POLYMER COMPOSITION, AND MOLDED OBJECT 三井化学株式会社 2023-01-05 WO disclosed
EP-4112671-A1 COPOLYMER FORMED BY RING-OPENING COPOLYMERIZATION OF CYCLOOLEFIN, COMPOSITION FOR INSULATING MATERIAL, AND INSULATING MATERIAL Zeon Corporation (JP) 2023-01-04 EP disclosed
US-5188875-A Adhering two disk substrates MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-02-23 US disclosed
US-5142007-A Copolymerizing with ethylene and at least one unsaturated monomer in presence of catalysts and mixed solvent MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-08-25 US disclosed
US-5140053-A Ring opened polymers derived from cycloolefins; heat and chemical resistant MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-08-18 US disclosed
EP-0482626-A2 Cycloolefin random copolymer composition and uses thereof MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-04-29 EP disclosed
US-5059487-A Cyclic olefin-olefin random copolymer MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-10-22 US disclosed
EP-0447072-A2 Cycloolefin random copolymer and process for preparing same MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-09-18 EP disclosed
EP-0446051-A1 Process for the production of cycloolefin-based random copolymer MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-09-11 EP disclosed
US-4990559-A Thermoplastic resin composition MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-02-05 US disclosed