Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1351502 | 0.87 | HDAC6 (0.44) | HDAC1HDAC6HDAC2HDAC8HDAC3 | |
| SCHEMBL1742487 | 0.78 | HDAC1 (0.51) | HDAC1LMNAHDAC6MEN1KMT2A | |
| SCHEMBL1349239 | 0.75 | PSMB1 (0.51) | HDAC1HDAC8 | |
| SCHEMBL19190193 | 0.75 | PSMB1 (0.51) | HDAC1HDAC8 | |
| SCHEMBL19190194 | 0.75 | HDAC1 (0.53) | HDAC1LMNAHDAC6MEN1KMT2A | |
| SCHEMBL1741779 | 0.74 | HDAC1 (0.47) | HDAC1LMNAHDAC6MEN1KMT2A | |
| SCHEMBL2134187 | 0.70 | CACNA1I (0.58) | HDAC1LMNAMEN1KMT2AHDAC2 | |
| SCHEMBL2134193 | 0.70 | CACNA1I (0.58) | HDAC1LMNAMEN1KMT2AHDAC2 | |
| SCHEMBL4927659 | 0.69 | HDAC6 (0.75) | HDAC1LMNAHDAC6MEN1KMT2A | |
| SCHEMBL1350324 | 0.67 | BCL2 (0.46) | HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2388247-B1 | Histone deacetylase inhibitors | UNIV TAIPEI MEDICAL (TW) | 2017-08-02 | — | — | EP | disclosed |
| EP-2388247-A2 | Histone deacetylase inhibitors | Taipei Medical University (TW) | 2011-11-23 | — | — | EP | disclosed |
| US-8039296-B2 | Organic thin film transistor array panel and manufacturing method thereof | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2011-10-18 | — | — | US | disclosed |