Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.51 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.44 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1349239 | 0.89 | PSMB1 (0.51) | HDAC1HDAC8PSMB1PSMB8PSMB9 | |
| SCHEMBL19190193 | 0.89 | PSMB1 (0.51) | HDAC1HDAC8PSMB1PSMB8PSMB9 | |
| SCHEMBL19190194 | 0.88 | HDAC1 (0.53) | HDAC1LMNAHDAC6HDAC2HDAC8 | |
| SCHEMBL1741779 | 0.81 | HDAC1 (0.47) | HDAC1LMNAHDAC6HDAC2HDAC8 | |
| SCHEMBL1353726 | 0.80 | PSMB1 (0.54) | HDAC1PSMB1PSMB8PSMB9PSMB5 | |
| SCHEMBL1349202 | 0.79 | PSMB1 (0.53) | HDAC1MEN1KMT2ASMN1; SMN2PSMB1 | |
| SCHEMBL1741783 | 0.78 | HDAC1 (0.47) | HDAC1LMNAHDAC6HDAC2HDAC8 | |
| SCHEMBL1350324 | 0.77 | BCL2 (0.46) | HDAC1HDAC8 | |
| SCHEMBL1350321 | 0.77 | BCL2 (0.46) | HDAC1HDAC8 | |
| SCHEMBL19190192 | 0.76 | LMNA (0.43) | HDAC1KLKB1LMNAHDAC6HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2388247-B1 | Histone deacetylase inhibitors | UNIV TAIPEI MEDICAL (TW) | 2017-08-02 | — | — | EP | disclosed |
| EP-2388247-A2 | Histone deacetylase inhibitors | Taipei Medical University (TW) | 2011-11-23 | — | — | EP | disclosed |
| US-8039296-B2 | Organic thin film transistor array panel and manufacturing method thereof | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2011-10-18 | — | — | US | disclosed |