Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.55 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.55 |
| ▸ | AR | P10275 | 6/20 | 0.55 |
| ▸ | PGR | P06401 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 2/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.55 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | SHBG | P04278 | 1/20 | 0.55 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.55 |
| ▸ | HRH2 | P25021 | 1/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6564735 | 0.89 | CYP3A4 (0.66) | MEN1KMT2ACYP3A4NR3C1AR | |
| SCHEMBL6564737 | 0.89 | CYP3A4 (0.66) | MEN1KMT2ACYP3A4NR3C1AR | |
| SCHEMBL6564740 | 0.89 | CYP3A4 (0.66) | MEN1KMT2ACYP3A4NR3C1AR | |
| Cismadinone SCHEMBL2111096 | 0.83 | HIF1A (0.52) | MEN1KMT2ACYP3A4NR3C1AR | |
| SCHEMBL6449571 | 0.81 | LMNA (0.65) | MEN1KMT2ACYP3A4NR3C1AR | |
| SCHEMBL6447018 | 0.81 | LMNA (0.65) | MEN1KMT2ACYP3A4NR3C1AR | |
| SCHEMBL11753048 | 0.80 | NR3C1 (0.80) | MEN1KMT2ACYP3A4NR3C1AR | |
| SCHEMBL11753058 | 0.80 | NR3C1 (0.80) | MEN1KMT2ACYP3A4NR3C1AR | |
| SCHEMBL11206531 | 0.80 | CYP3A4 (0.55) | MEN1KMT2ACYP3A4NR3C1AR | |
| SCHEMBL10810971 | 0.79 | CYP3A4 (0.61) | MEN1KMT2ACYP3A4NR3C1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160008376-A1 | Compositions, Methods and Uses for Treating Gender-Biased Immune Disorders | BIOCOPEA LIMITED (GB) | 2016-01-14 | — | — | US | claimed |
| WO-2016005599-A1 | COMPOSITIONS, METHODS AND USES FOR TREATING GENDER-BIASED IMMUNE DISORDERS | BIOCOPEA LIMITED (GB) | 2016-01-14 | — | — | WO | claimed |
| US-20160008376-A1 | Compositions, Methods and Uses for Treating Gender-Biased Immune Disorders | BIOCOPEA LIMITED (GB) | 2016-01-14 | — | — | US | disclosed |
| WO-2016005599-A1 | COMPOSITIONS, METHODS AND USES FOR TREATING GENDER-BIASED IMMUNE DISORDERS | BIOCOPEA LIMITED (GB) | 2016-01-14 | — | — | WO | disclosed |