SCHEMBL1742012

SCHEMBL1742012

CC(O)CCCCn1cnc2cncnc21

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.49
LTA4H P09960 1/20 0.43
HDAC1 Q13547 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
ADORA2A P29274 3/20 0.36
ADORA1 P30542 1/20 0.36
RPS6KA3 P51812 1/20 0.34
ALDH1A1 P00352 2/20 0.34
HSD17B10 Q99714 2/20 0.34
KDM4E B2RXH2 1/20 0.34
HPGD P15428 1/20 0.34
ADRA1A P35348 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34
DNMT3B Q9UBC3 1/20 0.33
CYP1A2 P05177 2/20 0.33
USP2 O75604 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
MAPK1 P28482 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10694872 0.81 FDPS (0.58) FDPSLTA4HHDAC1HDAC6ADORA2A
SCHEMBL10130693 0.81 FDPS (0.55) FDPSLTA4HHDAC1HDAC6ADORA2A
SCHEMBL28153339 0.81 FDPS (0.62) FDPSLTA4HHDAC1HDAC6ADORA2A
SCHEMBL3691691 0.81 FDPS (0.48) FDPSLTA4HHDAC1HDAC6ADORA2A
SCHEMBL8649807 0.80 FDPS (0.47) FDPSLTA4HHDAC1HDAC6ADORA2A
Hydrochloric Acid SCHEMBL28485022 0.80 FDPS (0.61) FDPSLTA4HHDAC1HDAC6ADORA2A
SCHEMBL8464130 0.80 FDPS (0.50) FDPSLTA4HHDAC1HDAC6ADORA2A
SCHEMBL6950642 0.79 ADORA2A (0.53) FDPSLTA4HHDAC1HDAC6ADORA2A
SCHEMBL8088086 0.78 FDPS (0.48) FDPSLTA4HHDAC1HDAC6ADORA2A
SCHEMBL8656700 0.78 FDPS (0.48) FDPSLTA4HHDAC1HDAC6ADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2389436-A2 STEM CELL CULTURE METHODS ITI Scotland Limited (GB) 2011-11-30 EP disclosed
US-20110257911-A1 SYSTEMS AND METHODS FOR DETECTING CHANGES IN ENERGY USAGE IN A BUILDING JOHNSON CONTROLS TECHNOLOGY COMPANY 2011-10-20 US disclosed