Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.58 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL364678 | 0.84 | FDPS (0.56) | FDPSLTA4HHDAC1HDAC6ALDH1A1 | |
| SCHEMBL10130693 | 0.84 | FDPS (0.55) | FDPSLTA4HHDAC1HDAC6ALDH1A1 | |
| SCHEMBL6259635 | 0.81 | FDPS (0.55) | FDPSLTA4HHDAC1HDAC6ALDH1A1 | |
| SCHEMBL30166038 | 0.81 | FDPS (0.55) | FDPSLTA4HHDAC1HDAC6ALDH1A1 | |
| SCHEMBL1742012 | 0.81 | FDPS (0.49) | FDPSLTA4HHDAC1HDAC6ALDH1A1 | |
| Water SCHEMBL27592739 | 0.80 | FDPS (0.54) | FDPSLTA4HHDAC1HDAC6ALDH1A1 | |
| SCHEMBL5324224 | 0.80 | FDPS (0.54) | FDPSLTA4HHDAC1HDAC6ALDH1A1 | |
| SCHEMBL9597540 | 0.78 | FDPS (0.55) | FDPSLTA4HHDAC1HDAC6ALDH1A1 | |
| SCHEMBL5017277 | 0.78 | FDPS (0.51) | FDPSLTA4HHDAC1HDAC6ALDH1A1 | |
| SCHEMBL4020843 | 0.78 | FDPS (0.51) | FDPSLTA4HHDAC1HDAC6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0270885-A1 | Synthesis of purin-9-ylalkylenoxymethyl phosphonic acids | Bristol-Myers Squibb Company (US) | 1988-06-15 | — | — | EP | disclosed |