1,6-Hexanediol

1,6-Hexanediol

SCHEMBL17420126

C=C(C)C(=O)OCCOCCOC(=O)C(=C)C.OCCCCCCO

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.63
TSHR P16473 6/20 0.56
HTT P42858 2/20 0.43
POLB P06746 1/20 0.43
APEX1 P27695 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
ALDH1A1 P00352 5/20 0.38
GAA P10253 1/20 0.37
CYP4F2 P78329 1/20 0.37
CYP4A11 Q02928 1/20 0.37
TP53 P04637 2/20 0.36
HIF1A Q16665 2/20 0.36
HSD17B10 Q99714 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
MAPT P10636 1/20 0.35
ACHE P22303 4/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,6-Hexanediol SCHEMBL9436385 1.00 THRB (0.63) THRBTSHRHTTPOLBAPEX1
1,4-Butanediol SCHEMBL16265704 0.98 THRB (0.66) THRBTSHRHTTPOLBAPEX1
SCHEMBL27530190 0.96 THRB (0.59) THRBTSHRHTTPOLBAPEX1
SCHEMBL27686916 0.96 THRB (0.59) THRBTSHRHTTPOLBAPEX1
SCHEMBL159921 0.96 THRB (0.59) THRBTSHRHTTPOLBAPEX1
1,4-Butanediol SCHEMBL14911112 0.94 THRB (0.61) THRBTSHRHTTPOLBAPEX1
SCHEMBL13397682 0.94 THRB (0.61) THRBTSHRHTTPOLBAPEX1
SCHEMBL8850641 0.94 THRB (0.61) THRBTSHRHTTPOLBAPEX1
SCHEMBL4238476 0.92 THRB (0.63) THRBTSHRHTTPOLBAPEX1
1,4-Butanediol SCHEMBL3252686 0.92 THRB (0.61) THRBTSHRHTTPOLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160009931-A1 ACTIVE ENERGY RAY-CURABLE INKJET INK, INK CONTAINER, AND INKJET DISCHARGING DEVICE RICOH COMPANY, LTD. (JP) 2016-01-14 US disclosed