⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38657816 | 0.93 | ACHE (0.34) | — | |
| SCHEMBL13556907 | 0.91 | ACHE (0.38) | — | |
| SCHEMBL20649140 | 0.87 | KDM4E (0.45) | — | |
| SCHEMBL3818094 | 0.84 | — | — | |
| SCHEMBL13818488 | 0.84 | — | — | |
| SCHEMBL11898330 | 0.84 | — | — | |
| SCHEMBL20456227 | 0.75 | ALDH1A1 (0.33) | — | |
| SCHEMBL2290317 | 0.74 | — | — | |
| SCHEMBL6248855 | 0.74 | — | — | |
| SCHEMBL24134623 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 225 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3723754-B1 | IMIDAZO [1,2-C] QUINAZOLIN-5-AMINE COMPOUNDS WITH A2A ANTAGONIST PROPERTIES | MERCK SHARP & DOHME LLC (US) | 2026-05-13 | — | — | EP | claimed |
| EP-4646207-A1 | COMPOSITIONS FOR HORMONALLY IMPACTED SKIN | The Boots Company PLC (GB) | 2025-11-12 | — | — | EP | claimed |
| CN-114585619-B | Alpha-D-galactopyranoside derivatives | 爱杜西亚药品有限公司 | 2024-09-27 | — | — | CN | claimed |
| WO-2024146869-A1 | COMPOSITIONS FOR HORMONALLY IMPACTED SKIN | THE BOOTS COMPANY PLC (GB) | 2024-07-11 | — | — | WO | claimed |
| WO-2024146870-A1 | COMPOSITIONS FOR HORMONALLY IMPACTED SKIN | THE BOOTS COMPANY PLC (GB) | 2024-07-11 | — | — | WO | claimed |
| EP-4054575-A1 | NOVEL METHOD | DSM IP Assets B.V. (NL) | 2022-09-14 | — | — | EP | claimed |
| US-10730851-B2 | Polymorph of triaryldimethylpiperazine dihydrochloride and preparation method and application thereof | YUNNAN INSTITUTE OF MATERIA MEDICA (CN) | 2020-08-04 | — | — | US | claimed |
| US-20190270720-A1 | POLYMORPH OF TRIARYLDIMETHYLPIPERAZINE DIHYDROCHLORIDE AND PREPARATION METHOD AND APPLICATION THEREOF | YUNNAN INSTITUTE OF MATERIA MEDICA (CN) | 2019-09-05 | — | — | US | claimed |
| EP-3324924-B1 | NOVEL SELECTIVE 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITORS | DSM IP ASSETS BV (NL) | 2019-08-21 | — | — | EP | claimed |
| US-9763938-B2 | Substituted quinoxalines as positive allosteric modulators of mGluR4 | MERCK PATENT GMBH (DE) | 2017-09-19 | — | — | US | claimed |
| EP-1604653-A1 | Acetylcholinesterase inhibitors for improving excretory potency of urinary bladder | Takeda Pharmaceutical Company Limited (JP) | 2005-12-14 | — | — | EP | claimed |
| EP-1554275-A2 | COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-07-20 | — | — | EP | claimed |
| US-20040220169-A1 | Carboxylic acid amides, the preparation thereof, and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-11-04 | — | — | US | claimed |
| US-20040176603-A1 | Substituted nitrogen-containing heterobicycles, the preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-09-09 | — | — | US | claimed |
| US-20040116457-A1 | Agents for improving excretory potency of urinary bladder | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-06-17 | — | — | US | claimed |
| US-20040063699-A1 | Gpr14 antagonist | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-04-01 | — | — | US | claimed |
| WO-2004013134-A2 | COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-02-12 | — | — | WO | claimed |
| EP-1310490-A1 | GPR14 ANTAGONIST | Takeda Chemical Industries, Ltd. (JP) | 2003-05-14 | — | — | EP | claimed |
| US-20020177593-A1 | Agents and crystals for improving excretory potency of urinary bladder | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2002-11-28 | — | — | US | claimed |
| EP-1118322-A1 | DRUGS FOR IMPROVING VESICAL EXCRETORY STRENGTH | Takeda Chemical Industries, Ltd. (JP) | 2001-07-25 | — | — | EP | claimed |