Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.31 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.31 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5612656 | 0.82 | CES2 (0.50) | CES2CES1HDAC8HDAC6GAA | |
| SCHEMBL5612649 | 0.82 | CES2 (0.50) | CES2CES1HDAC8HDAC6GAA | |
| SCHEMBL9709409 | 0.82 | CES2 (0.50) | CES2CES1HDAC8HDAC6GAA | |
| SCHEMBL165071 | 0.81 | CES2 (0.40) | CES2CES1HDAC8HDAC6GAA | |
| SCHEMBL27948175 | 0.81 | CES2 (0.46) | CES2CES1HDAC8HDAC6GAA | |
| SCHEMBL166347 | 0.81 | CES2 (0.40) | CES2CES1HDAC8HDAC6GAA | |
| SCHEMBL166346 | 0.81 | CES2 (0.40) | CES2CES1HDAC8HDAC6GAA | |
| SCHEMBL184066 | 0.79 | CES2 (0.55) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL1398377 | 0.79 | CES2 (0.55) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL20530262 | 0.79 | CES2 (0.55) | CES2CES1HDAC8HDAC6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4204406-A1 | ENRICHMENT OF A DIASTEREOMER IN MAGNOLAN | Symrise AG (DE) | 2023-07-05 | — | — | EP | disclosed |
| WO-2022042829-A1 | ENRICHMENT OF A DIASTEREOMER IN MAGNOLAN | SYMRISE AG (DE) | 2022-03-03 | — | — | WO | disclosed |
| WO-2022043089-A1 | ENRICHMENT OF A DIASTEREOMER IN MAGNOLAN | SYMRISE AG (DE) | 2022-03-03 | — | — | WO | disclosed |
| EP-3167031-A1 | ISOMER MIXTURES OF UNSATURATED MACROCYCLIC MUSK COMPOUNDS | Symrise AG (DE) | 2017-05-17 | — | — | EP | disclosed |
| WO-2016005361-A1 | ISOMER MIXTURES OF UNSATURATED MACROCYCLIC MUSK COMPOUNDS | SYMRISE AG (DE) | 2016-01-14 | — | — | WO | disclosed |
| WO-2016005360-A1 | MIXTURES HAVING ENRICHED E-ISOMERS OF UNSATURATED MACROCYCLIC MUSK COMPOUNDS | SYMRISE AG (DE) | 2016-01-14 | — | — | WO | disclosed |