Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | CCR1 | P32246 | 3/20 | 0.46 |
| ▸ | CCR5 | P51681 | 3/20 | 0.46 |
| ▸ | CCR8 | P51685 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL982910 | 0.85 | LMNA (0.58) | CYP3A4LMNAMAPTSMN1; SMN2NPC1 | |
| SCHEMBL29687953 | 0.85 | LMNA (0.58) | CYP3A4LMNAMAPTSMN1; SMN2NPC1 | |
| SCHEMBL28399164 | 0.84 | LMNA (0.56) | CYP3A4LMNAMAPTSMN1; SMN2NPC1 | |
| SCHEMBL28007273 | 0.79 | CCR1 (0.60) | CYP3A4LMNAMAPTSMN1; SMN2NPC1 | |
| SCHEMBL10787406 | 0.79 | LMNA (0.43) | CYP3A4LMNAMAPTSMN1; SMN2KDM4E | |
| SCHEMBL10025814 | 0.78 | KDM4E (0.55) | CYP3A4LMNAMAPTSMN1; SMN2NPC1 | |
| Phenanthrene SCHEMBL16685315 | 0.77 | CCR1 (0.76) | CYP3A4LMNAMAPTSMN1; SMN2NPC1 | |
| SCHEMBL686683 | 0.76 | LMNA (0.62) | CYP3A4LMNAMAPTSMN1; SMN2KDM4E | |
| SCHEMBL22320767 | 0.76 | LMNA (0.62) | CYP3A4LMNAMAPTSMN1; SMN2KDM4E | |
| SCHEMBL17228835 | 0.76 | CCR1 (0.60) | CYP3A4LMNAMAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105647520-A | New electroluminescent material and application thereof | 中节能万润股份有限公司 | 2016-06-08 | — | — | CN | disclosed |
| WO-2016005992-A1 | SUBSTITUTED NAPHTHO[2,1-b][1,10]PHENANTHROLINE BASED FLUORESCENT DYES AND APPLICATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-01-14 | — | — | WO | disclosed |