Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.56 |
| ▸ | CA2 | P00918 | 6/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | CA6 | P23280 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29435677 | 0.81 | TRPV4 (0.51) | CA1CA2CA9MAPK1LMNA | |
| SCHEMBL349118 | 0.81 | TRPV4 (0.51) | CA1CA2CA9MAPK1LMNA | |
| SCHEMBL31634218 | 0.79 | NFE2L2 (0.46) | CA1CA2CA9MAPK1LMNA | |
| SCHEMBL3704196 | 0.79 | COMT (0.47) | LMNANPC1HPGDHTTMEN1 | |
| SCHEMBL925929 | 0.79 | NFE2L2 (0.46) | CA1CA2CA9MAPK1LMNA | |
| SCHEMBL3698654 | 0.78 | COMT (0.46) | LMNANPC1HPGDHTTMEN1 | |
| SCHEMBL3698653 | 0.78 | NFE2L2 (0.45) | CA1CA2CA9MAPK1LMNA | |
| Lithium Ion SCHEMBL3698633 | 0.78 | NFE2L2 (0.45) | CA1CA2CA9MAPK1LMNA | |
| SCHEMBL3698635 | 0.78 | COMT (0.46) | LMNANPC1HPGDHTTMEN1 | |
| SCHEMBL3713453 | 0.78 | COMT (0.46) | LMNANPC1HPGDHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024115549-A1 | ARYL- AND HETEROARYL-SULFONAMIDE DERIVATIVES AS CCR8 MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2024-06-06 | — | — | WO | claimed |
| EP-0131861-A2 | 2-Substituted-3-sulfonamidepyridine compounds, process for preparing and pharmaceutical compositions comprising the same | FABRICA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS ABELLO, S.A. (ES) | 1985-01-23 | — | — | EP | claimed |
| WO-2024115549-A1 | ARYL- AND HETEROARYL-SULFONAMIDE DERIVATIVES AS CCR8 MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2024-06-06 | — | — | WO | disclosed |
| US-20210380548-A1 | Fused [1,2,4]Thiadiazine Derivatives Which Act as KAT Inhibitors of the MYST Family | CTXT PTY LIMITED (AU) | 2021-12-09 | — | — | US | disclosed |
| US-20210380548-A1 | Fused [1,2,4]Thiadiazine Derivatives Which Act as KAT Inhibitors of the MYST Family | CTXT PTY LIMITED (AU) | 2021-12-09 | — | — | US | disclosed |
| US-10844013-B2 | Phenyl amino piperidine mTORC inhibitors and uses thereof | NAVITOR PHARMACEUTICALS, INC. (US) | 2020-11-24 | — | — | US | disclosed |
| US-10844013-B2 | Phenyl amino piperidine mTORC inhibitors and uses thereof | NAVITOR PHARMACEUTICALS, INC. (US) | 2020-11-24 | — | — | US | disclosed |
| EP-3676266-A1 | FUSED [1,2,4]THIADIAZINE DERIVATIVES WHICH ACT AS KAT INHIBITORS OF THE MYST FAMILY | Ctxt Pty Ltd (AU) | 2020-07-08 | — | — | EP | disclosed |
| US-20200207716-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. | 2020-07-02 | — | — | US | disclosed |
| US-20200207716-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. | 2020-07-02 | — | — | US | disclosed |
| EP-3538091-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | Navitor Pharmaceuticals, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| US-4690707-A | PRE- AND POSTEMERGENCE HERBICIDES; PLANT GROWTH REGULATORS; PREFERENTIAL | CIBA-GEIGY CORPORATION (US) | 1987-09-01 | — | — | US | disclosed |
| US-4657578-A | Herbicidal ortho-heterocyclic sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-04-14 | — | — | US | disclosed |
| US-4643760-A | Herbicidal sulfonylureas | CIBA-GEIGY CORPORATION (US) | 1987-02-17 | — | — | US | disclosed |
| EP-0178101-A1 | Herbicidal ortho-heterocyclic sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-04-16 | — | — | EP | disclosed |
| US-4579583-A | HERBICIDES, GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1986-04-01 | — | — | US | disclosed |
| US-4549898-A | PREEMERGENT AND POSTEMERGENT HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1985-10-29 | — | — | US | disclosed |
| EP-0145664-A2 | Herbicidal sulfonyl ureas | CIBA-GEIGY AG (CH) | 1985-06-19 | — | — | EP | disclosed |
| EP-0103543-A2 | Sulfonyl ureas | CIBA-GEIGY AG (CH) | 1984-03-21 | — | — | EP | disclosed |
| EP-0097122-A2 | N-heterocyclosulfonyl-N'-pyrimidinyl and triazinyl ureas | CIBA-GEIGY AG (CH) | 1983-12-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210380548-A1 | Fused [1,2,4]Thiadiazine Derivatives Which Act as KAT Inhibitors of the MYST Family | KAT5, KAT6A, KAT2A | CA1 3478/4885CA2 4004/4885CA9 4651/4885 |
| US-10844013-B2 | Phenyl amino piperidine mTORC inhibitors and uses thereof | MTOR, RICTOR, RPTOR | CA1 4540/4885CA2 3770/4885CA9 4552/4885 |
| US-20200207716-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | MTOR, RICTOR, RPTOR | CA1 4540/4885CA2 3770/4885CA9 4552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.