⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17463503 | 0.90 | SLC5A1 (0.32) | — | |
| SCHEMBL14945996 | 0.90 | SLC5A1 (0.32) | — | |
| SCHEMBL14928761 | 0.90 | SLC5A1 (0.32) | — | |
| SCHEMBL15249044 | 0.90 | SLC5A1 (0.32) | — | |
| SCHEMBL18118104 | 0.90 | SLC5A1 (0.32) | — | |
| SCHEMBL15249043 | 0.74 | — | — | |
| SCHEMBL17463521 | 0.74 | — | — | |
| SCHEMBL15305383 | 0.74 | NNMT (0.30) | — | |
| SCHEMBL21082362 | 0.73 | SLC5A2 (0.36) | — | |
| SCHEMBL17210983 | 0.73 | SLC5A2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9233141-B2 | Modified polynucleotides for the production of proteins associated with blood and lymphatic disorders | MODERNA THERAPEUTICS, INC. (US) | 2016-01-12 | — | — | US | disclosed |