Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 8/20 | 0.39 |
| ▸ | NMT2 | O60551 | 7/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.37 |
| ▸ | NPY1R | P25929 | 2/20 | 0.37 |
| ▸ | NPY4R | P50391 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.34 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.34 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12035472 | 0.90 | NPY4R (0.46) | NMT1NMT2NPY5RNPY1RNPY4R | |
| SCHEMBL17424424 | 0.83 | CDYL2 (0.41) | NPY5RNPY1RNPY4RCHRNB2CHRNB4 | |
| SCHEMBL17424421 | 0.83 | CDYL2 (0.39) | NPY5RNPY1RNPY4RTSHRCHRNB2 | |
| SCHEMBL17424441 | 0.82 | NPY5R (0.42) | NMT1NMT2NPY5RNPY1RNPY4R | |
| SCHEMBL17424409 | 0.82 | NPY4R (0.40) | NMT1NMT2NPY5RNPY1RNPY4R | |
| SCHEMBL17424420 | 0.81 | NPY5R (0.43) | NMT1NMT2NPY5RNPY1RNPY4R | |
| SCHEMBL17424369 | 0.81 | SIRT5 (0.44) | NPY5RNPY1RNPY4R | |
| SCHEMBL17424413 | 0.81 | NPY5R (0.44) | NMT1NMT2NPY5RNPY1RNPY4R | |
| SCHEMBL17424422 | 0.79 | NPY4R (0.38) | NPY5RNPY1RNPY4R | |
| SCHEMBL17424362 | 0.78 | SMN1; SMN2 (0.39) | NMT1NMT2TSHRCPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9233086-B2 | Inhibition of WDR5 interaction with its binding partners | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2016-01-12 | — | — | US | disclosed |