Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | C1S | P09871 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SELL | P14151 | 1/20 | 0.33 |
| ▸ | SELP | P16109 | 1/20 | 0.33 |
| ▸ | SELE | P16581 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11237934 | 0.78 | ALDH1A1 (0.48) | ALDH1A1HPGDACHELMNACES2 | |
| SCHEMBL5568321 | 0.77 | TPMT (0.50) | TPMTPRSS1PRSS2C1SPRSS3 | |
| SCHEMBL27989860 | 0.75 | PARP1 (0.52) | HPGDACHEMEN1KMT2A | |
| SCHEMBL716226 | 0.74 | TPMT (0.48) | TPMTPRSS1PRSS2C1SPRSS3 | |
| SCHEMBL22991513 | 0.74 | CA1 (0.48) | ALDH1A1ACHELMNAMEN1CYP1A2 | |
| SCHEMBL22784010 | 0.74 | TPMT (0.38) | TPMTPRSS1PRSS2C1SPRSS3 | |
| SCHEMBL347092 | 0.72 | TPMT (0.59) | TPMTPRSS1PRSS2C1SPRSS3 | |
| SCHEMBL10419257 | 0.72 | TPMT (0.46) | TPMTPRSS1PRSS2C1SPRSS3 | |
| SCHEMBL9419478 | 0.72 | TPMT (0.46) | TPMTPRSS1PRSS2C1SPRSS3 | |
| SCHEMBL9071444 | 0.72 | PRSS1 (0.56) | TPMTPRSS1PRSS2C1SPRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2463269-B1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | INTREXON CORP (US) | 2016-09-28 | — | — | EP | disclosed |
| EP-2460786-B1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | INTREXON CORP (US) | 2016-01-13 | — | — | EP | disclosed |