Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | C1S | P09871 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21393194 | 0.79 | TPMT (0.35) | TPMTPRSS1PRSS2C1SPRSS3 | |
| SCHEMBL17424935 | 0.74 | TPMT (0.46) | TPMTPRSS1PRSS2C1SPRSS3 | |
| SCHEMBL716226 | 0.71 | TPMT (0.48) | TPMTPRSS1PRSS2C1SPRSS3 | |
| SCHEMBL9419478 | 0.69 | TPMT (0.46) | TPMTPRSS1PRSS2C1SPRSS3 | |
| SCHEMBL5568321 | 0.68 | TPMT (0.50) | TPMTPRSS1PRSS2C1SPRSS3 | |
| SCHEMBL21922915 | 0.67 | TPMT (0.35) | TPMTPRSS1PRSS2C1SPRSS3 | |
| SCHEMBL23847821 | 0.66 | TAS1R3 (0.32) | TPMTPRSS1PRSS2C1SPRSS3 | |
| SCHEMBL16953904 | 0.65 | TPMT (0.52) | TPMTPRSS1PRSS2C1SPRSS3 | |
| SCHEMBL2072660 | 0.65 | TPMT (0.52) | TPMTPRSS1PRSS2C1SPRSS3 | |
| SCHEMBL10419257 | 0.64 | TPMT (0.46) | TPMTPRSS1PRSS2C1SPRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200392138-A1 | PESTICIDALLY ACTIVE MESOIONIC HETEROCYCLIC COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200392138-A1 | PESTICIDALLY ACTIVE MESOIONIC HETEROCYCLIC COMPOUNDS | DDT, ACHE, MNS1 | TPMT 1227/4885PRSS1 3704/4885PRSS2 3285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.