Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4607962 | 0.82 | TP53 (0.35) | TP53 | |
| SCHEMBL15473838 | 0.82 | TP53 (0.35) | TP53 | |
| SCHEMBL13176566 | 0.80 | ALDH1A1 (0.35) | TP53 | |
| SCHEMBL17627863 | 0.79 | ALDH1A1 (0.32) | TP53 | |
| SCHEMBL15834916 | 0.79 | ALDH1A1 (0.32) | TP53 | |
| SCHEMBL14905652 | 0.74 | TP53 (0.31) | TP53 | |
| SCHEMBL14123059 | 0.72 | LMNA (0.36) | TP53 | |
| SCHEMBL12880101 | 0.72 | — | — | |
| SCHEMBL172872 | 0.72 | — | — | |
| SCHEMBL270417 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2678349-B1 | C-4\" POSITION SUBSTITUTED MACROLIDE DERIVATIVE | TAISHO PHARMACEUTICAL CO LTD (JP) | 2016-01-13 | — | — | EP | disclosed |