Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17425111 | 1.00 | ACHE (0.53) | ACHEEPHX1EPHX2TLR2 | |
| SCHEMBL17425147 | 0.93 | ACHE (0.55) | ACHEEPHX1EPHX2TLR2 | |
| SCHEMBL17425131 | 0.93 | ACHE (0.55) | ACHEEPHX1EPHX2TLR2 | |
| SCHEMBL7201630 | 0.91 | ACHE (0.59) | ACHEEPHX1EPHX2TLR2 | |
| SCHEMBL7200737 | 0.90 | ACHE (0.54) | ACHEEPHX1EPHX2TLR2 | |
| SCHEMBL17425144 | 0.88 | ACHE (0.54) | ACHEEPHX1EPHX2TLR2 | |
| SCHEMBL17425145 | 0.88 | ACHE (0.54) | ACHEEPHX1EPHX2TLR2 | |
| SCHEMBL17425148 | 0.84 | ACHE (0.56) | ACHEEPHX1EPHX2TLR2 | |
| SCHEMBL17425102 | 0.84 | ACHE (0.56) | ACHEEPHX1EPHX2TLR2 | |
| SCHEMBL7749335 | 0.81 | ACHE (0.70) | ACHEEPHX1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170204076-A1 | SYNTHESIS AND USE OF AMINO LIPIDS | SCREENFECT GMBH (DE) | 2017-07-20 | — | — | US | disclosed |
| US-20170204076-A1 | SYNTHESIS AND USE OF AMINO LIPIDS | SCREENFECT GMBH (DE) | 2017-07-20 | — | — | US | disclosed |
| EP-2966068-A1 | Synthesis and use of amino lipids | Incella GmbH (DE) | 2016-01-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170204076-A1 | SYNTHESIS AND USE OF AMINO LIPIDS | ACSL4, PYM1, LPAR4 | ACHE 2986/4885EPHX1 965/4885EPHX2 581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.