ACSL4

Long-chain-fatty-acid--CoA ligase 4 · O60488 · ACSL4 on Sugi Atlas →

0 patent compounds predicted against ACSL4, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to ACSL4 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Role of Pioglitazone in the Treatment of Non-alcoholic Steatohepatitis (NASH) PHASE4COMPLETED
The Impact of Omega-3 Supplementation on Gene Expression in Type 2 Diabetics PHASE4UNKNOWN
Comparison of Coenzyme A and Pantethine Capsule for Safety and Efficacy On Patients With Hyperlipidemia PHASE3COMPLETED
Metabolic Cofactor Supplementation in Obese Patients With Non-Alcoholic Fatty Liver Disease PHASE2COMPLETED
The Effects of Coenzyme A on Serum Lipids in Patients With Hyperlipidemia PHASE2COMPLETED
Effects of Short-term Perioperative Daidzein Intervention on Liver Histopathology in Patients With MASLD PHASE2NOT_YET_RECRUITING
The Effects of Coenzyme A Combined With Abiraterone on Patients With CRPC PHASE1/PHASE2UNKNOWN
Effect of Bezafibrate on Muscle Metabolism in Patients With Fatty Acid Oxidation Defects PHASE2COMPLETED
Acetylcarnitine and Insulin Sensitivity PHASE2COMPLETED
Liver Positron Emission Tomography (PET) Study of Non Alcoholic Fatty Liver Disease EARLY_PHASE1COMPLETED
Lifestyle Intervention in Preparation for Pregnancy (LIPP) nanCOMPLETED
Androgens and NAFLD Longitudinal Cohort Study nanRECRUITING
Fish Oil and Nonalcoholic Fatty Liver Disease (NAFLD) Study nanCOMPLETED
Fatty Acid Oxidation Defects and Insulin Sensitivity nanCOMPLETED
Fatty Acid Metabolism and Insulin Sensitivity: the Role of Endurance Exercise nanCOMPLETED
Molecular Mechanisms of Exercise Benefits to Insulin Resistant People nanCOMPLETED
De Novo Lipogenesis in Severity of NAFLD nanCOMPLETED
Familial Partial Lipodystrophy Study nanCOMPLETED
Use of MCT Oil for Enhancement of Weight Loss in Obese Patients nanCOMPLETED
Combining Gene Variants to Improve Risk Prediction for Metabolic (Dysfunction)- Associated Fatty Liver Disease and Its Progression to Cirrhosis in Indian Individuals With Type 2 Diabetes nanCOMPLETED
Role of Dairy Products in Weight Maintenance nanCOMPLETED
Impact Of Choline in Patients With NAFLD nanUNKNOWN
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes nanCOMPLETED
Screening of Healthy Adults for Genetic Variations That Control Fatty Acid Processing nanCOMPLETED
Genetic and Environmental Determinants of Triglycerides (GOLDN) nanCOMPLETED
NASH AMPK Exercise Dosing (AMPED) Trial nanRECRUITING
Systemic Biomarkers of Brain Injury From Hyperammonemia nanRECRUITING
Glycemic Index/Saturated Fatty Acid Diet and Hepatic Fat nanCOMPLETED
The Fasting Study - Unraveling the Mechanistic Effects of Prolonged Fasting in Humans. nanCOMPLETED
Exercise Intolerance Study in Long Chain Fatty Acid Oxidation Disorders nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a ACSL4 binder may also engage these)

ProteinNameSimilarity
O35547 1.000 O35547 →
Q9QUJ7 1.000 Q9QUJ7 →
Q9CZW4 1.000 Q9CZW4 →
ACSL3 Fatty acid CoA ligase Acsl3 1.000 landscape →
Q5R668 1.000 Q5R668 →
Q63151 1.000 Q63151 →
Q9CAP8 0.993 Q9CAP8 →
P30624 0.991 P30624 →
O60135 0.990 O60135 →
Q9P7D7 0.989 Q9P7D7 →
Q55DR6 0.989 Q55DR6 →
M4ISH1 0.988 M4ISH1 →
Q8LKS5 0.988 Q8LKS5 →
Q9SJD4 0.988 Q9SJD4 →
Q9T009 0.987 Q9T009 →
Q5FVE4 0.987 Q5FVE4 →
Q9C7W4 0.987 Q9C7W4 →
Q2XU92 0.987 Q2XU92 →
O22898 0.985 O22898 →
P47912 0.984 P47912 →
Q8LPS1 0.984 Q8LPS1 →
P39002 0.983 P39002 →
Q8JZR0 0.983 Q8JZR0 →
O88813 0.983 O88813 →
ACSL5 Long-chain-fatty-acid--CoA ligase 5 0.982 landscape →
Q9T0A0 0.982 Q9T0A0 →
Q9V3S9 0.982 Q9V3S9 →
O24146 0.982 O24146 →
Q7ZYC4 0.982 Q7ZYC4 →
O24540 0.981 O24540 →