SCHEMBL17425488

SCHEMBL17425488

CC1(C)c2ccccc2-c2ccc(-c3nc(-c4cccc(-c5ccc(-c6ccccc6)cc5)c4)nc(-c4cccc(-c5ccc(-c6ccccc6)cc5)c4)n3)cc21

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 16/20 0.46
RARA P10276 1/20 0.39
RARB P10826 1/20 0.39
RARG P13631 1/20 0.39
MEN1 O00255 1/20 0.38
ALDH1A1 P00352 1/20 0.38
MAPT P10636 1/20 0.38
HPGD P15428 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30021313 1.00 PDK2 (0.46) PDK2RARARARBRARGMEN1
SCHEMBL19009500 1.00 PDK2 (0.46) PDK2RARARARBRARGMEN1
SCHEMBL12133886 1.00 PDK2 (0.46) PDK2RARARARBRARGMEN1
SCHEMBL30103618 1.00 PDK2 (0.46) PDK2RARARARBRARGMEN1
SCHEMBL17425480 1.00 PDK2 (0.46) PDK2RARARARBRARGMEN1
SCHEMBL17151897 1.00 PDK2 (0.46) PDK2RARARARBRARGMEN1
SCHEMBL24648055 0.99 PDK2 (0.44) PDK2RARARARBRARGMEN1
SCHEMBL24952335 0.99 PDK2 (0.44) PDK2RARARARBRARGMEN1
SCHEMBL25141489 0.99 PDK2 (0.44) PDK2RARARARBRARGMEN1
SCHEMBL24872499 0.99 PDK2 (0.44) PDK2RARARARBRARGMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023100891-A1 SOLID MOLTEN MIXTURE, SOLID COMPOSITION, MIXED POWDER, METHOD FOR CHOOSING ORGANIC COMPOUND, METHOD FOR PRODUCING SOLID MOLTEN MIXTURE, AND METHOD FOR PRODUCING ORGANIC ELECTROLUMINESCENT ELEMENT 出光興産株式会社 2023-06-08 WO disclosed
US-20230130110-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-27 US disclosed
US-20230130110-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-27 US disclosed
EP-4167707-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2023-04-19 EP disclosed
EP-3591728-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2022-12-14 EP disclosed
US-20210257554-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-08-19 US disclosed
US-11024811-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-06-01 US disclosed
US-20190259957-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-08-22 US disclosed
US-10297762-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-05-21 US disclosed
US-20160028021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-01-28 US disclosed
US-20160028021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-01-28 US disclosed
EP-2966706-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2016-01-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160028021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OR10J3 PDK2 1226/4885RARA 3245/4885RARB 3616/4885
US-20190259957-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SOD1, PIEZO1, L1CAM PDK2 1298/4885RARA 2888/4885RARB 3032/4885
US-20210257554-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SOD1, PIEZO1, L1CAM PDK2 1298/4885RARA 2888/4885RARB 3032/4885
US-11024811-B2 Organic electroluminescent materials and devices SOD1, PIEZO1, L1CAM PDK2 1298/4885RARA 2888/4885RARB 3032/4885
US-20230130110-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SOD1, PIEZO1, L1CAM PDK2 1298/4885RARA 2888/4885RARB 3032/4885
US-10297762-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OR10J3 PDK2 1226/4885RARA 3245/4885RARB 3616/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.