SCHEMBL17426232

SCHEMBL17426232

CCc1cc2c(ccc3c2ccc2c4cc(CC)oc4ccc23)o1

nearest known ligand 0.47

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 17/20 0.47
HTR2A P28223 8/20 0.47
SLC22A12 Q96S37 3/20 0.45
HTR2B P41595 7/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12279059 1.00 HTR2C (0.47) HTR2CHTR2ASLC22A12HTR2B
SCHEMBL12279097 0.87 PAX8 (0.45) HTR2CHTR2ASLC22A12HTR2B
SCHEMBL13561824 0.83 HTR2C (0.40) HTR2CHTR2ASLC22A12HTR2B
SCHEMBL12278147 0.83 STS (0.47) HTR2CHTR2ASLC22A12
SCHEMBL17426184 0.83 STS (0.47) HTR2CHTR2ASLC22A12
SCHEMBL17426199 0.79 ALOX15 (0.53)
SCHEMBL12278162 0.79 ALOX15 (0.53)
SCHEMBL13561836 0.79 CYP1A2 (0.41) HTR2CHTR2ASLC22A12HTR2B
SCHEMBL17426110 0.78 ALOX15 (0.59)
SCHEMBL12278166 0.78 ALOX15 (0.59)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160013429-A1 ORGANIC THIN FILM TRANSISTOR FUJIFILM CORPORATION (JP) 2016-01-14 US disclosed
US-20160013429-A1 ORGANIC THIN FILM TRANSISTOR FUJIFILM CORPORATION (JP) 2016-01-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160013429-A1 ORGANIC THIN FILM TRANSISTOR SCN8A, SLC8A1, NTRK1 HTR2C 3282/4885HTR2A 3080/4885SLC22A12 498/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.