Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.37 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17428262 | 0.93 | GAA (0.35) | L3MBTL1GAASCN9A | |
| SCHEMBL17428266 | 0.93 | GAA (0.35) | GAASCN9A | |
| SCHEMBL17428274 | 0.92 | NAAA (0.38) | — | |
| SCHEMBL17428247 | 0.91 | KMT2A (0.41) | KMT2AL3MBTL1GAA | |
| SCHEMBL17428043 | 0.91 | KMT2A (0.41) | KMT2AL3MBTL1GAA | |
| SCHEMBL17428264 | 0.90 | KMT2A (0.37) | KMT2AL3MBTL1GAA | |
| SCHEMBL17428271 | 0.90 | KMT2A (0.38) | KMT2AL3MBTL1GAASCN9A | |
| SCHEMBL17245245 | 0.89 | KMT2A (0.39) | ABHD6DAGLAKMT2AL3MBTL1KCNH2 | |
| SCHEMBL17428053 | 0.86 | KMT2A (0.40) | KMT2AL3MBTL1GAA | |
| SCHEMBL17428054 | 0.84 | KMT2A (0.38) | KMT2AL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9955691-B2 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2018-05-01 | — | — | US | disclosed |
| US-9955691-B2 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2018-05-01 | — | — | US | disclosed |
| US-20160007601-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC | 2016-01-14 | — | — | US | disclosed |
| US-20160007601-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC | 2016-01-14 | — | — | US | disclosed |
| WO-2016007529-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2016-01-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160007601-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | CYP4F12, CYP1A2, FKBP2 | ABHD6 1635/4885DAGLA 2382/4885KMT2A 3234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.