Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 6/20 | 0.62 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.58 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29434614 | 0.88 | GRIN2B (0.53) | GRIN2BMTNR1AMTNR1BSIGMAR1PRMT5 | |
| SCHEMBL255286 | 0.88 | GRIN2B (0.53) | GRIN2BMTNR1AMTNR1BSIGMAR1PRMT5 | |
| Bicarbonate SCHEMBL2441660 | 0.86 | GRIN2B (0.51) | GRIN2BMTNR1AMTNR1BSIGMAR1PRMT5 | |
| Hydrochloric Acid SCHEMBL10493696 | 0.86 | GRIN2B (0.51) | GRIN2BMTNR1AMTNR1BSIGMAR1PRMT5 | |
| Bromide SCHEMBL9725911 | 0.86 | GRIN2B (0.51) | GRIN2BMTNR1AMTNR1BSIGMAR1PRMT5 | |
| SCHEMBL12656430 | 0.86 | GRIN2B (0.56) | GRIN2BMTNR1AMTNR1BMAOAMAOB | |
| Glycine SCHEMBL2438253 | 0.82 | GRIN2B (0.47) | GRIN2BMTNR1AMTNR1BSIGMAR1CA1 | |
| SCHEMBL18983605 | 0.82 | CA1 (0.58) | GRIN2BCA1CA2 | |
| Hydrochloric Acid SCHEMBL9545036 | 0.82 | MTNR1A (0.56) | GRIN2BMTNR1AMTNR1BMAOAMAOB | |
| Hydrochloric Acid SCHEMBL9545040 | 0.82 | MTNR1A (0.56) | GRIN2BMTNR1AMTNR1BMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2387571-A1 | OXADIAZOLE DERIVATIVES AS SLPL RECEPTOR AGONISTS | Almirall S.A. (ES) | 2011-11-23 | — | — | EP | claimed |
| US-8041930-B2 | Data processing apparatus and method for controlling thread access of register sets when selectively operating in secure and non-secure domains | ARM LIMITED (GB) | 2011-10-18 | — | — | US | claimed |
| WO-2010081692-A1 | OXADIAZOLE DERIVATIVES AS SLPL RECEPTOR AGONISTS | ALMIRALL, S.A. (ES) | 2010-07-22 | — | — | WO | claimed |
| EP-2387571-A1 | OXADIAZOLE DERIVATIVES AS SLPL RECEPTOR AGONISTS | Almirall S.A. (ES) | 2011-11-23 | — | — | EP | disclosed |
| US-8041930-B2 | Data processing apparatus and method for controlling thread access of register sets when selectively operating in secure and non-secure domains | ARM LIMITED (GB) | 2011-10-18 | — | — | US | disclosed |
| WO-2010081692-A1 | OXADIAZOLE DERIVATIVES AS SLPL RECEPTOR AGONISTS | ALMIRALL, S.A. (ES) | 2010-07-22 | — | — | WO | disclosed |
| US-4521607-A | HYPOTENSIVE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-06-04 | — | — | US | disclosed |
| EP-0035868-A1 | Bicyclic compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1981-09-16 | — | — | EP | disclosed |