Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | AADAC | P22760 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15354225 | 0.94 | ENPP2 (0.44) | ARCYP3A4CES2ABCB11ALDH1A1 | |
| SCHEMBL12947044 | 0.94 | ENPP2 (0.44) | ARCYP3A4CES2ABCB11ALDH1A1 | |
| SCHEMBL10062911 | 0.93 | MAPT (0.39) | ALDH1A1LMNAGLAMAPK1SMN1; SMN2 | |
| SCHEMBL17429224 | 0.90 | ENPP2 (0.45) | ARCYP3A4CES2ABCB11ALDH1A1 | |
| SCHEMBL10062740 | 0.90 | ENPP2 (0.45) | ARCYP3A4CES2ABCB11ALDH1A1 | |
| SCHEMBL12916716 | 0.89 | NPC1 (0.43) | ARCYP3A4CES2ABCB11ALDH1A1 | |
| SCHEMBL15727677 | 0.88 | SIRT6 (0.46) | ARCYP3A4CES2ABCB11ALDH1A1 | |
| SCHEMBL12916720 | 0.88 | EPHX2 (0.43) | ARCYP3A4ENPP2PGREPHX2 | |
| SCHEMBL15354209 | 0.88 | EPHX2 (0.43) | ARCYP3A4ENPP2PGREPHX2 | |
| SCHEMBL12947292 | 0.88 | ENPP2 (0.40) | ARCYP3A4CES2ABCB11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016005576-A1 | USE OF ANTHELMINTIC AGENTS AGAINST DIROFILARIA IMMITIS | INTERVET INTERNATIONAL B.V. (NL) | 2016-01-14 | — | — | WO | disclosed |