SCHEMBL17429751

SCHEMBL17429751

CCc1csc(C(Cc2ccc(NS(=O)(=O)O)cc2)NC(=O)C(Cc2ccccc2)c2cccc(CO)c2)n1

nearest known ligand 0.69

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTPRB P23467 20/20 0.69
PTPN1 P18031 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL684313 1.00 PTPRB (0.69) PTPRBPTPN1
SCHEMBL468124 0.93 PTPRB (0.77) PTPRBPTPN1
SCHEMBL20474090 0.93 PTPRB (0.77) PTPRBPTPN1
SCHEMBL468123 0.93 PTPRB (0.77) PTPRBPTPN1
SCHEMBL28828125 0.91 PTPRB (0.73) PTPRB
SCHEMBL29794269 0.91 PTPRB (0.73) PTPRB
SCHEMBL678605 0.91 PTPRB (0.73) PTPRB
SCHEMBL678606 0.91 PTPRB (0.73) PTPRB
SCHEMBL29794267 0.90 PTPRB (0.75) PTPRBPTPN1
SCHEMBL500551 0.90 PTPRB (0.75) PTPRBPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160008327-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR PREVENTING METASASIS OF CANCER CELLS EyePoint, Inc. 2016-01-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160008327-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR PREVENTING METASASIS OF CANCER CELLS TSG101, MMP8, EPCAM PTPRB 841/4885PTPN1 2384/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.