SCHEMBL17430666

SCHEMBL17430666

CC/C(Cc1ccc(Sc2ccccc2)cc1)=N\OC(=O)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.43
MAPT P10636 4/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
HPGD P15428 1/20 0.41
KLF5 Q13887 2/20 0.40
NR2F2 P24468 1/20 0.40
PAX8 Q06710 1/20 0.40
NPC1 O15118 5/20 0.39
RAB9A P51151 5/20 0.39
CDK5 Q00535 3/20 0.39
CDK5R1 Q15078 3/20 0.39
PKM P14618 3/20 0.39
MITF O75030 1/20 0.39
TNF P01375 1/20 0.39
NOD1 Q9Y239 1/20 0.39
KDM4E B2RXH2 1/20 0.37
LMNA P02545 1/20 0.37
GAA P10253 1/20 0.37
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29501294 0.84 ALDH1A1 (0.46) ALDH1A1MAPTSMN1; SMN2HPGDKLF5
SCHEMBL29501293 0.80 MAPT (0.51) ALDH1A1MAPTSMN1; SMN2HPGDKLF5
SCHEMBL245812 0.78 ALDH1A1 (0.45) ALDH1A1MAPTSMN1; SMN2HPGDKLF5
SCHEMBL14429957 0.78 ALDH1A1 (0.45) ALDH1A1MAPTSMN1; SMN2HPGDKLF5
SCHEMBL29201237 0.78 ALDH1A1 (0.45) ALDH1A1MAPTSMN1; SMN2HPGDKLF5
SCHEMBL28486023 0.78 ALDH1A1 (0.42) ALDH1A1MAPTSMN1; SMN2HPGDKLF5
SCHEMBL20935416 0.76 ALDH1A1 (0.46) ALDH1A1MAPTSMN1; SMN2HPGDKLF5
SCHEMBL14024276 0.75 CES2 (0.45) ALDH1A1HPGDGAAKMT2AMEN1
SCHEMBL2910298 0.74 MEN1 (0.41) ALDH1A1MAPTSMN1; SMN2HPGDKDM4E
SCHEMBL20578374 0.73 ALDH1A1 (0.43) ALDH1A1MAPTSMN1; SMN2HPGDKLF5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160011509-A1 PHOTOSENSITIVE RESIN COMPOSITION FOR BLACK MATRIX, BLACK MATRIX, COLOR FILTER AND METHOD FOR MANUFACTURING THE SAME, AND LIQUID CRYSTAL DISPLAY APPARATUS CHI MEI CORPORATION (TW) 2016-01-14 US disclosed