Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CHKA | P35790 | 7/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | NCF1 | P14598 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18879716 | 0.94 | CHKA (0.50) | ALDH1A1KDM4EMAPTCHKAMC4R | |
| SCHEMBL18876445 | 0.85 | HRH3 (0.46) | ALDH1A1KDM4EMAPTCHKAMC4R | |
| SCHEMBL18879756 | 0.85 | HRH3 (0.47) | ALDH1A1KDM4EMAPTCHKANCF1 | |
| SCHEMBL18970043 | 0.84 | ALDH1A1 (0.48) | ALDH1A1KDM4EMAPTCHKAMC4R | |
| SCHEMBL17432251 | 0.84 | CHKA (0.45) | ALDH1A1KDM4EMAPTCHKAMC4R | |
| Hydrochloric Acid SCHEMBL17423414 | 0.82 | CHKA (0.44) | ALDH1A1KDM4EMAPTCHKAMC4R | |
| SCHEMBL20584234 | 0.82 | KDM4E (0.43) | ALDH1A1KDM4EMAPTCHKAMC4R | |
| SCHEMBL17432248 | 0.79 | ALDH1A1 (0.46) | ALDH1A1KDM4EMAPTCHKALMNA | |
| SCHEMBL23808267 | 0.78 | CHKA (0.54) | ALDH1A1KDM4EMAPTCHKAMC4R | |
| SCHEMBL17432212 | 0.77 | WDR5 (0.45) | MAPTCHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016006975-A2 | NOVEL IMIDAZOTRIAZINONE OR IMIDAZOPYRAZINONE DERIVATIVES, AND USE THEREOF | ST PHARM CO., LTD. (KR) | 2016-01-14 | — | — | WO | disclosed |