Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.68 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | KIF11 | P52732 | 4/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9771151 | 0.92 | SLC6A3 (0.81) | SLC6A4SLC6A3CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL16012142 | 0.81 | SLC6A4 (0.66) | SLC6A4SLC6A3CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL16011789 | 0.81 | SLC6A4 (1.00) | SLC6A4SLC6A3CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7428364 | 0.81 | SLC6A3 (0.66) | SLC6A4SLC6A3CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7439094 | 0.80 | SLC6A3 (1.00) | SLC6A4SLC6A3CYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL7438013 | 0.78 | SLC6A3 (0.96) | SLC6A4SLC6A3CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9829609 | 0.75 | SLC6A3 (0.79) | SLC6A4SLC6A3CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL19939782 | 0.75 | CHRNA7 (0.41) | SLC6A4SLC6A3CYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL9771072 | 0.74 | SLC6A3 (0.76) | SLC6A4SLC6A3CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL16011814 | 0.69 | SLC6A3 (0.47) | SLC6A4SLC6A3CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160009644-A1 | POTENT AND SELECTIVE INHIBITORS OF MONOAMINE TRANSPORTERS; METHOD OF MAKING; AND USE THEREOF | The United States of America, as represented by th Secretary, Department of Health and Human Service (US) | 2016-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160009644-A1 | POTENT AND SELECTIVE INHIBITORS OF MONOAMINE TRANSPORTERS; METHOD OF MAKING; AND USE THEREOF | SLC6A2, SLC6A4, SLC6A3 | SLC6A4 2/4885SLC6A3 3/4885CYP1A2 580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.