Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 3/20 | 1.00 |
| ▸ | SLC6A4 | P31645 | 2/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 2/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 2/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 2/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | HRH1 | P35367 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7438013 | 0.98 | SLC6A3 (0.96) | SLC6A3SLC6A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9771151 | 0.90 | SLC6A3 (0.81) | SLC6A3SLC6A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9829609 | 0.89 | SLC6A3 (0.79) | SLC6A3SLC6A4CYP1A2CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL9771072 | 0.87 | SLC6A3 (0.76) | SLC6A3SLC6A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11013503 | 0.87 | SLC6A3 (0.77) | SLC6A3SLC6A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9217623 | 0.80 | SLC6A4 (0.66) | SLC6A3SLC6A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL17432205 | 0.80 | SLC6A4 (0.68) | SLC6A3SLC6A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9865463 | 0.80 | SLC6A4 (0.67) | SLC6A3SLC6A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL16011789 | 0.78 | SLC6A4 (1.00) | SLC6A3SLC6A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL16012142 | 0.78 | SLC6A4 (0.66) | SLC6A3SLC6A4CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0097546-B1 | BENZHYDRYLSULFINYL ETHYL AMINES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THERAPY | LABORATOIRE L. LAFON Société anonyme dite: (FR) | 1985-09-25 | — | — | EP | claimed |
| EP-0097546-A1 | Benzhydrylsulfinyl ethyl amines, process for their preparation and their use in therapy | LABORATOIRE L. LAFON Société anonyme dite: (FR) | 1984-01-04 | — | — | EP | claimed |
| US-11555013-B2 | Potent and selective inhibitors of monoamine transporters; method of making; and use thereof | THE USA, AS REPRESENTED BY THE SECRETARY, DHHS (US) | 2023-01-17 | — | — | US | disclosed |
| EP-2964611-B1 | POTENT AND SELECTIVE INHIBITORS OF MONOAMINE TRANSPORTERS; METHOD OF MAKING; AND USE THEREOF | US HEALTH (US) | 2022-10-19 | — | — | EP | disclosed |
| EP-2964611-B1 | POTENT AND SELECTIVE INHIBITORS OF MONOAMINE TRANSPORTERS; METHOD OF MAKING; AND USE THEREOF | US HEALTH (US) | 2022-10-19 | — | — | EP | disclosed |
| US-20210130288-A1 | POTENT AND SELECTIVE INHIBITORS OF MONOAMINE TRANSPORTERS; METHOD OF MAKING; AND USE THEREOF | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2021-05-06 | — | — | US | disclosed |
| US-20210130288-A1 | POTENT AND SELECTIVE INHIBITORS OF MONOAMINE TRANSPORTERS; METHOD OF MAKING; AND USE THEREOF | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2021-05-06 | — | — | US | disclosed |
| US-10913711-B2 | Potent and selective inhibitors of monoamine transporters; method of making; and use thereof | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2021-02-09 | — | — | US | disclosed |
| US-10913711-B2 | Potent and selective inhibitors of monoamine transporters; method of making; and use thereof | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2021-02-09 | — | — | US | disclosed |
| US-10590074-B2 | Potent and selective inhibitors of monoamine transporters; method of making; and use thereof | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2020-03-17 | — | — | US | disclosed |
| US-10590074-B2 | Potent and selective inhibitors of monoamine transporters; method of making; and use thereof | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2020-03-17 | — | — | US | disclosed |
| US-5171752-A | BENZHYDRYL DERIVATIVES HAVING CALMODULIN INHIBITOR PROPERTIES | AKZO N.V. (NL) | 1992-12-15 | — | — | US | disclosed |
| EP-0467435-A2 | Benzhydryl derivatives having calmodulin inhibitor properties | Akzo Nobel N.V. (NL) | 1992-01-22 | — | — | EP | disclosed |
| EP-0302896-B1 | N-(W-SUBSTITUTED ALKYL)-N'-[(IMIDAZOLE-4-YL)ALKYL]GUANIDINE | CEDONA PHARMACEUTICALS B.V. (NL) | 1991-08-14 | — | — | EP | disclosed |
| US-5010095-A | Antiallergens, congestive heart failure | CEDONA PHARMACEUTICALS B.V. (NL) | 1991-04-23 | — | — | US | disclosed |
| EP-0135160-B1 | BISAMIDE BISTHIOL COMPOUNDS USEFUL FOR MAKING TECHNETIUM RADIODIAGNOSTIC RENAL AGENTS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1989-04-26 | — | — | EP | disclosed |
| EP-0302896-A1 | N-(W-SUBSTITUTED ALKYL)-N'-[(IMIDAZOLE-4-YL)ALKYL]GUANIDINE. | CEDONA PHARM BV (NL) | 1989-02-15 | — | — | EP | disclosed |
| WO-1987007891-A1 | N-(2-SUBSTITUTED ALKYL)-N'-[(IMIDAZOLE-4-YL)ALKYL]GUANIDINE | CEDONA PHARMACEUTICALS B.V. (NL) | 1987-12-30 | — | — | WO | disclosed |
| EP-0097546-B1 | BENZHYDRYLSULFINYL ETHYL AMINES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THERAPY | LABORATOIRE L. LAFON Société anonyme dite: (FR) | 1985-09-25 | — | — | EP | disclosed |
| EP-0097546-A1 | Benzhydrylsulfinyl ethyl amines, process for their preparation and their use in therapy | LABORATOIRE L. LAFON Société anonyme dite: (FR) | 1984-01-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10590074-B2 | Potent and selective inhibitors of monoamine transporters; method of making; and use thereof | SLC6A2, SLC6A4, SLC6A3 | SLC6A3 3/4885SLC6A4 2/4885CYP1A2 580/4885 |
| US-20210130288-A1 | POTENT AND SELECTIVE INHIBITORS OF MONOAMINE TRANSPORTERS; METHOD OF MAKING; AND USE THEREOF | SLC6A2, SLC6A4, SLC6A3 | SLC6A3 3/4885SLC6A4 2/4885CYP1A2 580/4885 |
| US-11555013-B2 | Potent and selective inhibitors of monoamine transporters; method of making; and use thereof | SLC6A2, SLC6A4, SLC6A3 | SLC6A3 3/4885SLC6A4 2/4885CYP1A2 580/4885 |
| US-10913711-B2 | Potent and selective inhibitors of monoamine transporters; method of making; and use thereof | SLC6A2, SLC6A4, SLC6A3 | SLC6A3 3/4885SLC6A4 2/4885CYP1A2 580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.