Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.50 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.50 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | ECE1 | P42892 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | KDM5C | P41229 | 2/20 | 0.41 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20415450 | 1.00 | LMNA (0.50) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| SCHEMBL12491912 | 1.00 | LMNA (0.50) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| SCHEMBL5035377 | 1.00 | LMNA (0.50) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| SCHEMBL162041 | 1.00 | LMNA (0.50) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Hydrochloric Acid SCHEMBL8650017 | 0.97 | LMNA (0.47) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Hydrochloric Acid SCHEMBL6306661 | 0.97 | LMNA (0.47) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Hydrochloric Acid SCHEMBL496928 | 0.97 | LMNA (0.47) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| SCHEMBL109879 | 0.97 | LMNA (0.53) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| SCHEMBL28473579 | 0.93 | LMNA (0.50) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Hydrochloric Acid SCHEMBL4199437 | 0.93 | LMNA (0.50) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160009657-A1 | AMINE-CONTAINING LIPIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160009657-A1 | AMINE-CONTAINING LIPIDS AND USES THEREOF | PHOSPHO1, CHMP4B, SGMS1 | LMNA 402/4885EGLN1 3494/4885ALKBH5 331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.