Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | APEX1 | P27695 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | RARB | P10826 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16541710 | 0.97 | THRB (0.56) | HTTPOLBAPEX1TDP1THRB | |
| SCHEMBL17190956 | 0.93 | THRB (0.60) | HTTPOLBAPEX1TDP1THRB | |
| SCHEMBL19157855 | 0.91 | HTT (0.49) | HTTPOLBAPEX1TDP1THRB | |
| SCHEMBL17301215 | 0.89 | HTT (0.53) | HTTPOLBAPEX1TDP1THRB | |
| SCHEMBL12172631 | 0.89 | THRB (0.63) | HTTTHRBTSHRHPGDCYP3A4 | |
| SCHEMBL9517527 | 0.87 | POLB (0.53) | HTTPOLBAPEX1TDP1THRB | |
| SCHEMBL17433312 | 0.87 | THRB (0.53) | HTTPOLBAPEX1TDP1THRB | |
| SCHEMBL11035951 | 0.87 | POLB (0.53) | HTTPOLBAPEX1TDP1THRB | |
| SCHEMBL14400544 | 0.87 | HTT (0.73) | HTTPOLBAPEX1TDP1THRB | |
| SCHEMBL22597442 | 0.87 | HTT (0.54) | HTTPOLBAPEX1TDP1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10040997-B2 | Nematic liquid crystal composition and liquid crystal display element including same | DIC CORPORATION (JP) | 2018-08-07 | — | — | US | disclosed |
| US-20180187079-A1 | COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME | DIC CORPORATION (JP) | 2018-07-05 | — | — | US | disclosed |
| US-20180187079-A1 | COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME | DIC CORPORATION (JP) | 2018-07-05 | — | — | US | disclosed |
| US-20160319191-A1 | NEMATIC LIQUID-CRYSTAL COMPOSITION AND LIQUID-CRYSTAL DISPLAY ELEMENT OBTAINED USING SAME | DIC CORPORATION (JP) | 2016-11-03 | — | — | US | disclosed |
| US-20160319191-A1 | NEMATIC LIQUID-CRYSTAL COMPOSITION AND LIQUID-CRYSTAL DISPLAY ELEMENT OBTAINED USING SAME | DIC CORPORATION (JP) | 2016-11-03 | — | — | US | disclosed |
| US-20160215215-A1 | NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT INCLUDING SAME | DIC CORPORATION (JP) | 2016-07-28 | — | — | US | disclosed |
| US-20160215215-A1 | NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT INCLUDING SAME | DIC CORPORATION (JP) | 2016-07-28 | — | — | US | disclosed |
| US-20160009999-A1 | NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DEVICE USING THE SAME | DIC CORPORATION (JP) | 2016-01-14 | — | — | US | disclosed |
| US-20160009999-A1 | NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DEVICE USING THE SAME | DIC CORPORATION (JP) | 2016-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10040997-B2 | Nematic liquid crystal composition and liquid crystal display element including same | LBR, NCAPD3, CCT4 | HTT 2932/4885POLB 2264/4885APEX1 4397/4885 |
| US-20160215215-A1 | NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT INCLUDING SAME | NCAPD3, LBR, CCT4 | HTT 2590/4885POLB 2265/4885APEX1 4236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.