Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9517527 | 1.00 | POLB (0.53) | POLBHTTTDP1APEX1THRB | |
| SCHEMBL21644463 | 0.98 | THRB (0.51) | POLBHTTTDP1APEX1THRB | |
| SCHEMBL14028578 | 0.94 | THRB (0.55) | POLBHTTTDP1APEX1THRB | |
| SCHEMBL346370 | 0.91 | POLB (0.62) | POLBHTTTDP1APEX1ALDH1A1 | |
| SCHEMBL246239 | 0.91 | THRB (0.55) | POLBHTTTDP1THRBALDH1A1 | |
| SCHEMBL11132915 | 0.88 | THRB (0.55) | POLBHTTTDP1THRBALDH1A1 | |
| SCHEMBL17433302 | 0.87 | HTT (0.58) | POLBHTTTDP1APEX1THRB | |
| SCHEMBL21154699 | 0.87 | TSHR (0.59) | POLBHTTTDP1THRBALDH1A1 | |
| SCHEMBL7623776 | 0.87 | POLB (0.58) | POLBHTTTDP1APEX1ALDH1A1 | |
| SCHEMBL7630968 | 0.87 | THRB (0.51) | POLBHTTTDP1THRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4436764-A | Method and apparatus for surface-hardening treatment of synthetic resin shaped articles | MITSUBISHI RAYON COMPANY, LTD. (JP) | 1984-03-13 | — | — | US | disclosed |