SCHEMBL17433308

SCHEMBL17433308

C=C(C)C(=O)Oc1ccc(COc2ccc(OC(=O)C(=C)C)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 7/20 0.53
ELANE P08246 1/20 0.53
MAOA P21397 1/20 0.51
PARP10 Q53GL7 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.49
ALDH1A1 P00352 1/20 0.49
HTT P42858 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
KMT2A Q03164 1/20 0.49
ATM Q13315 1/20 0.49
NPC1 O15118 1/20 0.49
POLB P06746 1/20 0.49
RAB9A P51151 1/20 0.49
RXRA P19793 1/20 0.49
RXRB P28702 1/20 0.49
PTPRC P08575 1/20 0.49
PTPN2 P17706 1/20 0.49
PTPN1 P18031 1/20 0.49
ALOX5 P09917 1/20 0.48
PTGS1 P23219 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22596477 0.95 MAOB (0.49) MAOBELANEMAOAPARP10SMN1; SMN2
SCHEMBL22596640 0.95 MAOB (0.49) MAOBELANEMAOAPARP10SMN1; SMN2
SCHEMBL22566528 0.90 ELANE (0.56) MAOBELANEMAOARXRARXRB
SCHEMBL22566506 0.87 THRB (0.50) MAOBELANEMAOAPARP10SMN1; SMN2
SCHEMBL22566464 0.87 THRB (0.50) MAOBELANEMAOAPARP10SMN1; SMN2
SCHEMBL22566608 0.87 THRB (0.50) MAOBELANEMAOAPARP10SMN1; SMN2
SCHEMBL13891748 0.86 ELANE (0.51) MAOBELANESMN1; SMN2ALDH1A1HTT
SCHEMBL17145182 0.86 ELANE (0.53) MAOBELANEMAOASMN1; SMN2ALDH1A1
SCHEMBL18675330 0.85 HTT (0.54) MAOBELANEMAOAPARP10SMN1; SMN2
SCHEMBL2680055 0.85 PARP10 (0.47) MAOBELANEMAOAPARP10SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11773327-B2 PSA-type liquid crystal composition and display device having same JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2023-10-03 US disclosed
US-11773327-B2 PSA-type liquid crystal composition and display device having same JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2023-10-03 US disclosed
US-20200332195-A1 PSA-TYPE LIQUID CRYSTAL COMPOSITION AND DISPLAY DEVICE HAVING SAME JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2020-10-22 US disclosed
US-10040997-B2 Nematic liquid crystal composition and liquid crystal display element including same DIC CORPORATION (JP) 2018-08-07 US disclosed
US-10040997-B2 Nematic liquid crystal composition and liquid crystal display element including same DIC CORPORATION (JP) 2018-08-07 US disclosed
US-20180187079-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME DIC CORPORATION (JP) 2018-07-05 US disclosed
US-20180187079-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME DIC CORPORATION (JP) 2018-07-05 US disclosed
US-20160319191-A1 NEMATIC LIQUID-CRYSTAL COMPOSITION AND LIQUID-CRYSTAL DISPLAY ELEMENT OBTAINED USING SAME DIC CORPORATION (JP) 2016-11-03 US disclosed
US-20160319191-A1 NEMATIC LIQUID-CRYSTAL COMPOSITION AND LIQUID-CRYSTAL DISPLAY ELEMENT OBTAINED USING SAME DIC CORPORATION (JP) 2016-11-03 US disclosed
US-20160215215-A1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT INCLUDING SAME DIC CORPORATION (JP) 2016-07-28 US disclosed
US-20160215215-A1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT INCLUDING SAME DIC CORPORATION (JP) 2016-07-28 US disclosed
EP-3029126-A1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC Corporation (JP) 2016-06-08 EP disclosed
US-20160009999-A1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DEVICE USING THE SAME DIC CORPORATION (JP) 2016-01-14 US disclosed
US-20160009999-A1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DEVICE USING THE SAME DIC CORPORATION (JP) 2016-01-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10040997-B2 Nematic liquid crystal composition and liquid crystal display element including same LBR, NCAPD3, CCT4 MAOB 4747/4885ELANE 2426/4885MAOA 4522/4885
US-20160215215-A1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT INCLUDING SAME NCAPD3, LBR, CCT4 MAOB 4788/4885ELANE 2419/4885MAOA 4568/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.