Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 2/20 | 0.69 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.66 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.66 |
| ▸ | TYR | P14679 | 1/20 | 0.66 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.66 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.66 |
| ▸ | SHBG | P04278 | 1/20 | 0.63 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.62 |
| ▸ | ABL1 | P00519 | 2/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.57 |
| ▸ | BCR | P11274 | 2/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MIF | P14174 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30176916 | 0.81 | HIF1A (0.52) | CALCRLPTPN1ABCB1NPC1CYP3A4 | |
| SCHEMBL28887391 | 0.81 | HIF1A (0.52) | CALCRLPTPN1ABCB1NPC1CYP3A4 | |
| SCHEMBL10800535 | 0.80 | PTPN1 (0.77) | CALCRLPDE4BPDE4DTYRPTGS1 | |
| Moracin M SCHEMBL1740981 | 0.80 | PDE4D (1.00) | CALCRLPDE4BPDE4DTYRPTGS1 | |
| Moracin M SCHEMBL29979946 | 0.80 | PDE4D (1.00) | CALCRLPDE4BPDE4DTYRPTGS1 | |
| SCHEMBL4404220 | 0.80 | CYP3A4 (0.80) | ABCB1ALOX5MEN1KMT2ANPC1 | |
| SCHEMBL28843685 | 0.80 | MIF (0.80) | PTGS1MEN1KMT2AMIFNPC1 | |
| SCHEMBL20147031 | 0.79 | CALCRL (0.74) | CALCRLPDE4BPDE4DTYRPTGS1 | |
| SCHEMBL28792949 | 0.79 | CASP3 (0.63) | ALOX5MEN1KMT2ANPC1RAB9A | |
| SCHEMBL29742911 | 0.79 | CASP3 (0.63) | ALOX5MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104447646-B | A kind of method complete synthesis for natural product Moracin M | 中科院广州化学有限公司 | 2016-08-31 | — | — | CN | claimed |
| CN-104447646-A | Total synthesis method for natural product Moracin M | CAS GUANGZHOU CHEMISTRY CO LTD | 2015-03-25 | — | — | CN | claimed |
| EP-2388255-A1 | Polysubstituted benzofurans and medicinal applications thereof | Ikerchem, S.L. (ES) | 2011-11-23 | — | — | EP | claimed |
| US-8038466-B1 | Power receptacle with enlarged heat dissipation path formed on mating face and power connector assembly thereof | ALLTOP ELECTRONICS (SUZHOU) CO., LTD (CN) | 2011-10-18 | — | — | US | claimed |
| CN-115181082-B | Synthetic method of natural molecule Moracin M | 江苏集萃分子工程研究院有限公司 | 2023-11-03 | — | — | CN | disclosed |
| CN-112358459-B | Preparation method of benzofuran compound | 心远(广州)药物研究有限公司 | 2023-01-17 | — | — | CN | disclosed |
| CN-115181082-A | Synthetic method of natural molecule Moracin M | 江苏集萃分子工程研究院有限公司 | 2022-10-14 | — | — | CN | disclosed |
| CN-112358459-A | Preparation method of benzofuran compound | 心远(广州)药物研究有限公司 | 2021-02-12 | — | — | CN | disclosed |
| CN-110894192-A | Preparation method of benzofuran compound | 心远(广州)药物研究有限公司 | 2020-03-20 | — | — | CN | disclosed |
| CN-104447646-B | A kind of method complete synthesis for natural product Moracin M | 中科院广州化学有限公司 | 2016-08-31 | — | — | CN | disclosed |
| CN-104447646-A | Total synthesis method for natural product Moracin M | CAS GUANGZHOU CHEMISTRY CO LTD | 2015-03-25 | — | — | CN | disclosed |
| EP-2388255-A1 | Polysubstituted benzofurans and medicinal applications thereof | Ikerchem, S.L. (ES) | 2011-11-23 | — | — | EP | disclosed |
| EP-2388255-A1 | Polysubstituted benzofurans and medicinal applications thereof | Ikerchem, S.L. (ES) | 2011-11-23 | — | — | EP | disclosed |
| US-8038466-B1 | Power receptacle with enlarged heat dissipation path formed on mating face and power connector assembly thereof | ALLTOP ELECTRONICS (SUZHOU) CO., LTD (CN) | 2011-10-18 | — | — | US | disclosed |