Moracin M

Moracin M

SCHEMBL1740981

Oc1cc(O)cc(-c2cc3ccc(O)cc3o2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4D Q08499 3/20 1.00
PTGS1 P23219 2/20 1.00
PDE4B Q07343 2/20 1.00
TYR P14679 1/20 1.00
PTGS2 P35354 1/20 1.00
SHBG P04278 1/20 0.76
CALCRL Q16602 2/20 0.74
ALOX5 P09917 2/20 0.56
ALOX15 P16050 2/20 0.56
ALOX12 P18054 2/20 0.56
XDH P47989 2/20 0.56
PTPN1 P18031 1/20 0.56
ESR2 Q92731 2/20 0.55
ESR1 P03372 1/20 0.55
APP P05067 2/20 0.54
FLT3 P36888 1/20 0.50
HDAC6 Q9UBN7 1/20 0.49
CA12 O43570 2/20 0.48
CA1 P00915 2/20 0.48
CA9 Q16790 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Moracin M SCHEMBL29979946 1.00 PDE4D (1.00) PDE4DPTGS1PDE4BTYRPTGS2
SCHEMBL9138143 0.86 SHBG (1.00) PDE4DPTGS1PDE4BTYRPTGS2
SCHEMBL20473143 0.83 SHBG (0.79) PDE4DPTGS1PDE4BTYRPTGS2
Stemofuran A SCHEMBL28792809 0.81 TYR (0.68) PDE4DPTGS1PDE4BTYRPTGS2
Stemofuran A SCHEMBL29742935 0.81 TYR (0.68) PDE4DPTGS1PDE4BTYRPTGS2
SCHEMBL734501 0.80 SHBG (0.80) PDE4DPTGS1PDE4BTYRPTGS2
SCHEMBL733973 0.80 SHBG (0.80) PDE4DPTGS1PDE4BTYRPTGS2
SCHEMBL30176923 0.80 SHBG (0.80) PDE4DPTGS1PDE4BTYRPTGS2
SCHEMBL1743359 0.80 CALCRL (0.69) PDE4DPTGS1PDE4BTYRPTGS2
SCHEMBL30879576 0.78 PTGS1 (0.65) PDE4DPTGS1PDE4BTYRPTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120131618-A Application of morin M in preparation of medicines for treating peripheral neuritis 哈尔滨医科大学 2025-06-13 CN claimed
CN-119950478-A Application of moracin M in preparation of anti-enterovirus medicines 江汉大学 2025-05-09 CN claimed
CN-117843654-A Cortex mori extract with uric acid reducing and kidney protecting activities as well as preparation method and application thereof 山东省农业科学院 2024-04-09 CN claimed
CN-117462535-A Application of moracin M in preparation of medicines for inhibiting formation of bacterial biofilm 复旦大学附属中山医院 2024-01-30 CN claimed
CN-115181082-B Synthetic method of natural molecule Moracin M 江苏集萃分子工程研究院有限公司 2023-11-03 CN claimed
CN-114948932-B Use of a composition comprising mulberenone for the preparation of a product for the prevention and treatment of hair loss by acting on the hair follicle tissue 浩溪(海南)生物科技有限公司 2023-05-30 CN claimed
CN-115181082-A Synthetic method of natural molecule Moracin M 江苏集萃分子工程研究院有限公司 2022-10-14 CN claimed
WO-2022131604-A1 ANTIVIRAL COMPOSITION CONTAINING RAMULUS-MORI-DERIVED COMPOUND AS ACTIVE INGREDIENT 한국한의학연구원 2022-06-23 WO claimed
CN-106008172-B Preparation method and application of effective part with tyrosinase inhibition effect in mulberry twigs 江南大学 2019-06-07 CN claimed
CN-106632199-A Method for extracting tyrosinase activity inhibition substances from dendrobium candidum 翟珺 2017-05-10 CN claimed
CN-104447646-B A kind of method complete synthesis for natural product Moracin M 中科院广州化学有限公司 2016-08-31 CN claimed
CN-104447646-A Total synthesis method for natural product Moracin M CAS GUANGZHOU CHEMISTRY CO LTD 2015-03-25 CN claimed
EP-2388255-A1 Polysubstituted benzofurans and medicinal applications thereof Ikerchem, S.L. (ES) 2011-11-23 EP claimed
US-8038466-B1 Power receptacle with enlarged heat dissipation path formed on mating face and power connector assembly thereof ALLTOP ELECTRONICS (SUZHOU) CO., LTD (CN) 2011-10-18 US claimed
US-20260083663-A1 BOTANICAL COMPOSITIONS AND METHODS OF PRODUCTION AND USE THEREOF ARKANSAS STATE UNIV JONESBORO (US) 2026-03-26 US disclosed
US-12507703-B2 Methods, devices and compositions for preserving human milk THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2025-12-30 US disclosed
CN-120960197-A Application of moracin M in preparation of anti-HSV-1 drugs 江汉大学 2025-11-18 CN disclosed
US-6737439-B2 ACTIVE CANCER CHEMOPREVENTATIVE AND TREATING AGENTS IN MAMMALS, INCLUDING HUMANS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2004-05-18 US disclosed
US-20030125377-A1 Aromatase inhibitors from Broussonetia papyrifera BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS THE 2003-07-03 US disclosed
WO-2003013554-A2 AROMATASE INHIBITORS FROM BROUSSONETIA PAPYRIFERA THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2003-02-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030125377-A1 Aromatase inhibitors from Broussonetia papyrifera CYP19A1, HSD17B11, CYP17A1 PDE4D 1069/4885PTGS1 35/4885PDE4B 506/4885
US-12507703-B2 Methods, devices and compositions for preserving human milk LPL, CEL, LPO PDE4D 855/4885PTGS1 4638/4885PDE4B 1224/4885
US-20260083663-A1 BOTANICAL COMPOSITIONS AND METHODS OF PRODUCTION AND USE THEREOF SAMM50, SYMPK, CD69 PDE4D 2150/4885PTGS1 2972/4885PDE4B 2108/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.